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Browsing by Author "Cagin, Y.F."

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Protective Effects of Apocynin on Cisplatin-induced Hepatotoxicity in Rats

Cagin, Y.F.; Erdogan, M.A.; Sahin, N.; Parlakpinar, H.; Atayan, Y.; Polat, A.; Vardi, N.; Yildiz, A.; Tanbek, K. (2015)

Background and Aims: Despite it being a highly potent antineoplastic drug, cisplatin has important toxic adverse effects limiting its use such as nephrotoxicity, neurotoxicity and ototoxicity. It is thought that cisplatin-induced ...
Relationship of percutaneous endoscopic gastrostomy-related mortality and morbidity rates and effectiveness with advancing age

Cagin, Y.F.; Atayan, Y.; Erdogan, M.A.; Bilgic, Y. (2015)

Background and aims: Percutaneous endoscopic gastrostomy (PEG) is insertion of a tube to stomach through abdominal wall for provision of nutrition in patients who couldn’t be fed by oral route. In the present study, it was ...
Could platelet indices be prognostic biomarkers for mild or severe acute pancreatitis?

Bilgic, Y.; Akbulut, S.; Kutlu, O.; Colak, C.; Yilmaz, C.; Seckin, Y.; Cagin, Y.F.; Harputluoglu, M.; Erkurt, M.A.; Yildirim, O. (2016)

The aim of this study was to show the relation of platelet indices with the severity of acute pancreatitis (AP) and if they have any correlation with the severity of AP. Forty-seven patients with AP hospitalized in Department ...
Beneficial effects of dexpanthenol on mesenteric ischemia and reperfusion injury in experimental rat model

Cagin, Y.F.; Atayan, Y.; Sahin, N.; Parlakpinar, H.; Polat, A.; Vardi, N.; Tagluk, M.E.; Tanbek, K.; Yildiz, A. (2016)

Background and aim It has been reported that intestinal ischemia-reperfusion (I/R) injury results from oxidative stress caused by increased reactive oxygen species. Dexpanthenol (Dxp) is an alcohol analogue with epitelization, ...
Association of eNOS Gene Polymorphisms G894T and T-786C with Risk of Hepatorenal Syndrome

Seckin, Y.; Yigit, A.; Yesilada, E.; Gulbay, G.; Cagin, Y.F.; Gozukara, H.; Bilgic, Yi.; Yildirim, O.; Turkoz, Y.; Aksungur, Z. (2016)

Background. There are no studies investigating the relationship between endothelial nitric oxide synthase (eNOS) gene polymorphisms and hepatorenal syndrome (HRS). Aim. The purpose of this study is to elucidate whether ...
Incidence and clinical presentation of portal vein thrombosis in cirrhotic patients

Cagin, Y.F.; Atayan, Y.; Erdogan, M.A.; Dagtekin, F.; Colak, C. (2016)

Background Portal vein thrombosis (PVT) is due to many risk factors, but its pathogenesis is still not clearly understood. To identify the risk factors for PVT, we analyzed the clinical characteristics and complications ...
The Acute Effect of Humic Acid on Iron Accumulation in Rats

Cagin, Y.F.; Sahin, N.; Polat, A.; Erdogan, M.A.; Atayan, Y.; Eyol, E.; Bilgic, Y.; Seckin, Y.; Colak, C. (2016)

Free iron leads to the formation of pro-oxidant reactive oxygen species (ROS). Humic acids (HAs) enhance permeability of cellular wall and act as a chelator through electron transferring. This study was designed to test ...
The role of the eNOS G894T and T-786C gene polymorphism in the development of ascites in cirrhosis

Yildirim, O.; Yigit, A.; Seckin, Y.; Yesilada, E.; Gulbay, G.; Cagin, Y.F.; Aksungur, Z.; Bilgic, Y.; Türkoz, Y.; Yologlu, S. (2016)

Objective: Increased nitric oxide (NO) production in cirrhotic patients causes splanchnic vasodilation, leading to the development of the hyperdynamic circulatory syndrome. One factor that influences plasma NO concentration ...
The protective effects of apocynin on ionizing radiation-induced intestinal damage in rats

Cagin, Y.F.; Parlakpinar, H.; Polat, A.; Vardi, N.; Atayan, Y.; Erdogan, M.A.; Ekici, K.; Yildiz, A.; Sarihan, M.E.; Aladag, H. (2016)

Background and aims: Radiation colitis typically emerges during radiotherapy of intraabdominal malignancies. While the underlying mechanism remains unclear, it is considered that free oxygen radicals act like cellular ...
Effects of dexpanthenol on acetic acid-induced colitis in rats

Cagin, Y.F.; Parlakpinar, H.; Vardi, N.; Polat, A.; Atayan, Y.; Erdogan, M.A.; Tanbek, K. (2016)

While the pathogenesis of acetic acid (AA)-induced colitis is unclear, reactive oxygen species are considered to have a significant effect. The aim of the present study was to elucidate the therapeutic potential of ...
Nucleotide-Binding Oligomerization Domain-Containing Protein 2 Variants in Patients with Spontaneous Bacterial Peritonitis

Harputluoglu, M.M.M.; Dertli, R.; Otlu, B.; Demirel, U.; Yener, O.; Bilgic, Y.; Erdogan, M.A.; Atayan, Y.; Cagin, Y.F. (2016)

Background: The occurrence of spontaneous bacterial peritonitis (SBP) is significantly increased in carriers of nucleotide-binding oligomerization domain-containing protein 2 (NOD2) variants, suggesting that local immune ...
Association of CagA-positive Helicobacter pylori infection with severity of obstructive sleep apnea syndrome

Yildirim, O.; Bali, I.; Tulubas, F.; Mete, R.; Topcu, B.; Seckin, Y.; Cagin, Y.F.; Bilgic, Y.; Alp, R. (2016)

Aim: To investigate the association between Helicobacter pylori cytotoxin-associated gene-A (CagA) status and the severity of OSA syndrome in infected patients. Methods: Ninty-six patients with obstructive sleep apnea ...
Acute toxic hepatitis induced by a herbal medicine : Anchusa Boraginaceae

Cagin, Y.F.; Seckin, Y.; Firat, F.; Samdanci, E. (2017)

BACKGROUND AND AIM: Herbal treatments are becoming increasingly popular in many countries. Anchusa Boraginaceae (also called Tort plant and beef tongue) is commonly used as a herbal medicine in Elazıg region as diuretic ...
Albendazole induced recurrent acute toxic hepatitis: A case report

Bilgic, Y.; Yilmaz, C.; Cagin, Y.F.; Atayan, Y.; Karadag, N.; Harputluoglu, M.M.M. (2017)

Introduction: Drug induced acute toxic hepatitis can be idiosyncratic. Albendazole, a widely used broad spectrum antiparasitic drug is generally accepted as a safe drug. It may cause asymptomatic transient liver enzyme ...
Comparison of patients with fulminant versus near-miss fulminant drug-induced hepatitis

Bilgic, Y.; Akbulut, S.; Kutlu, O.; Yilmaz, C.; Colak, C.; Deviren, M.V.; Cagin, Y.F.; Seckin, Y.; Yildirim, O.; Harputluoglu, M. (2017)

This study aimed to investigate and compare clinical and laboratory properties of patients with fulminant versus near-miss fulminant drug-induced hepatitis and the effect of these properties on mortality. Drug-induced ...
Drug induced autoimmune hepatitis: A single center experience

Bilgic, Y.; Harputluoglu, H.; Yilmaz, C.; Karadag, N.; Cagin, Y.F.; Akbulut, S.; Seckin, Y.; Kutlu, O.; Yildirim, O.; Harputluoglu, M. (2017)

Objective: Many drugs such as minocycline, nitrofurantoin, halothane, non-steroidal anti-inflammatory drugs, anti TNF (Tumor Necrosis Factor) antagonists can induce the autoimmune hepatitis. Herein, we aimed to assess ...
Effects of renal replacement therapy on fibromyalgia syndrome in patients with chronic kidney disease

Berber, I.; Sahin, I.; Gorgel, A.; Cagin, Y.F.; Bag, H.G.; Berber, N.K. (2018)

Introduction: Although musculoskeletal disorders are among the major complications of chronic kidney disease (CKD), there are scarce data to investigate fibromyalgia syndrome (FMS) in these patients. We aimed to investigate ...
A mitochondrial neurogastrointestinal encephalomyopathy with intestinal pseudo-obstruction resulted from a novel splice site mutation

Erdogan, M.A.; Seckin, Y.; Harputluoglu, M.M.; Karincaoglu, M.; Aladag, M.; Caliskan, A.R.; Bilgic, Y.; Yildirim, O.; Cagin, Y.F.; Atayan, Y.; Cengiz, A.N.; Emul, C.; Esener, Z.; Erbay, M.F.; Tekedereli, I. (2019)

Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is an autosomal recessive disorder characterized by gastrointestinal dysmotility, cachexia, ptosis, peripheral neuropathy and leukoencephalopathy. The diagnosis ...
Early therapeutic plasma exchange may improve treatment outcomes in severe acute toxic Hepatitis

Berber, I.; Cagin, Y.F.; Erdogan, M.A.; Ataman, E.; Gozukara, H.; Erkurt, M.A.; Yildirim, O.; Kuku, İ.; Kaya, E.; Bilgic, Y.; Sarici, A.; Bicim, S.; Polat, A. (2021)

Background and objectives: Acute toxic hepatitis can result in a different clinical course from a completely curable disease to subacute hepatitis, chronic hepatitis, and fulminant hepatitis failure, which is quite mortal. ...
Protective effects of apocynin against ionizing radiation-induced hepatotoxicity in rats

Cagin, Y.F.; Parlakpinar, H.; Vardi, N.; Aksanyar, S. (2022)

Radiation hepatotoxicity is thought to be due to free oxygen radicals. We investigated the protective effects of apocynin (APO) against ionizing radiation induced oxidative stress in liver tissue following whole body ...

Now showing items 1-20 of 21

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