İnönü Üniversitesi Kurumsal Akademik Arşivi
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Güncel Gönderiler
Correlation of lipid profiles with coronary artery plaque levels in patients undergoing coronary angiography
(İnönü Üniversitesi, 2024) Uzunpolat Yayla, Sedanur; Demi̇r Akca, Ayse Semra; Çakır, Mustafa Ozan; Turmus, Gözde Nur; Yayla, Abdulkerim; Karanfi̇l, Sema Soner; Ci̇msi̇r Soran, Tuğba
This study aims to observe the effect of lipid profiles (total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride (TG)) on coronary artery plaque rates of patients undergoing coronary angiography at Zonguldak Bülent Ecevit University (ZBEUN) Health Practice and Research Hospital. A total of 500 patients who underwent coronary angiography (CAG) between January 2019 and December 2020 at ZBEUN Health Practice and Research Hospital participated in this retrospective study. The sample of this study consists of 250 patients with a stenosis level below 50% and 250 patients with stenosis level of 50% and above according to CAG results. Information and data about the patients were accessed through the Hospital Information Management System (HIMS). The mean age of the individuals participating in the study was 63 years, the mean age of women was 65±12.3, and the mean age of men was 62±11.8. The majority of patients are men (74.2%). When we categorized the lipid profiles as low, optimal and high, LDL, triglyceride and total cholesterol values were found to be significantly higher and HDL values were found to be significantly lower in those with a stenosis degree of 50% and above (p<0.001). While the rate of those with a stenosis degree of 50% and above was found to be higher in the age groups of 55-64 and over 80 years (60.1% and 57.8%, respectively), the rate of those with a stenosis degree below 50% was found to be higher in other age groups. No significant difference was detected between lipid profiles according to gender and age. It is well known that dyslipidemia increases coronary artery risk and its treatment reduces cardiovascular events and mortality in patients at high risk for cardiovascular diseases. The increase in LDL, TG, total cholesterol levels and the decrease in HDL levels caused an increase in the level of coronary artery plaque.
Geçmişten Günümüze Hadisleri Bir Araya Getirme Çabaları ve el-Mudevvenetü’l-Câmi’a Adlı Hadis Projesi
(İnönü Üniversitesi, 2024) Yıldırım, Selahattin
Tarihte, hadisleri hatırlama, kolayca bulma ve ortak özellikleri barındıran hadisleri toplu olarak görmek amacıyla çeşitli çalışmalar yapılmıştır. İlk dönemlerden itibaren \etrâf
ST Segment Yükselmeli Miyokard İnfarktüsü Olan Hastalarda Modifiye Sistemik İmmün İnflamasyon İndeksi ile Kontrastın Neden Olduğu Nefropati Arasındaki İlişki
(İnönü Üniversitesi, 2024) Bayramoğlu, Adil
Developing contrast induced nephropathy after primary PCI in patients with ST segment elevation myocardial infarction is a risky condition in terms of mortality and morbidity. Various studies have shown that the systemic inflammatory index predicts (SII) the development of CIN. Mean platelet volume (MPV) is an important indicator known to be associated with the platelet function and activation. Therefore, we revised SII and named it modified SII (mSII) by using NLR multiply MPV. Material and Methods: This study includes patients who underwent pPCI due to STEMI in our cardiology department between February 2015 and February 2021. Modified SII was obtained by using MPV instead of platelet in the formula (mSII= NLR x MPV). Patients who underwent pPCI with STEMI were divided into two groups, those with CIN and those without CIN, and compared. Informed consent was obtained from all patients. Results: In the logistic regression analysis, it was observed that the mSII, NLR, GFR and contrast medium amount was independent predictor of CIN. The optimal threshold mSII for predicting CIN was >42.5, with a 78.1% sensitivity and 52.3% specificity ([AUC]: 0.639, 95%CI: 0.602- 0.674, p< 0.001). Pairwise comparison of ROC curves, it was observed that the predictive value of mSII for the development of CIN was better than NLR. (z-test = 3.144, P = 0.001) Conclusion: We think that mSII, which we have shown to be superior to SII in predicting the development of CIN and is very easy to calculate, is a parameter that can be considered in predicting the development of CIN after pPCI in STEMI patients.
Can Mean Platelet Volume be an Inflammatory Marker in Pediatric Diabetic Ketoacidosis?
(İnönü Üniversitesi, 2024) Trabzon, Gül; Çiçek, Dilek; Güllü, Şeyma Demiray; Yazarlı, Esra; Güllü, Ufuk Utku; El, Çiğdem
This study explores the association between mean platelet volume (MPV) and other hematological parameters in children with diabetic ketoacidosis (DKA), aiming to identify hematological changes and their implications for management and treatment strategies in pediatric type 1 diabetes mellitus (T1DM). In a retrospective, two-center analysis of 323 children, participants were categorized into three groups: DKA, T1DM without ketoacidosis, and healthy controls (95). Hematological parameters and HbA1c levels were collected. Blood pH levels classified DKA severity, and statistical analyses included One-way ANOVA, correlation tests, receiver operating characteristic curve analysis, and logistic regression to assess the predictive value of hematological parameters for DKA. No significant demographic differences were noted among the groups. Patients with DKA exhibited significantly lower MPV and higher neutrophil-to-lymphocyte ratio (NLR) compared with both patients with T1DM without ketoacidosis and healthy controls. Logistic regression showed MPV ≤9.35 and NLR ≥2.73 significantly increased DKA risk. This study demonstrated a significant relationship between DKA and altered hematological parameters (MPV and NLR) in pediatric patients, highlighting their potential as markers for early detection and risk assessment of DKA.
The effect of arthroscopic Bankart repair and remplissage procedure on joint range of motion and functional outcomes in anterior shoulder instability
(İnönü Üniversitesi, 2024) Yılmaz, Sinan; Bozkurt, İbrahim; Öçgüder, Durmuş Ali
This study aimed to investigate the effect of arthroscopic Bankart repair (ABR) alone and ABR with an additional remplissage procedure on joint range of motion and functional results in patients with anterior shoulder instability. Methods: This retrospective study included patients treated 1 year ago with either ABR alone or the ABR additional remplissage pro- cedure. The Bankart lesion was determined by magnetic resonance imaging, and the amount of glenoid bone loss was determined by computed tomography. Patients with glenoid bone loss <25% and on-track Hill–Sachs lesions (HSLs) were treated with ABR alone (22 females, 8 males; mean age = 27.4 ± 6.4 years). Those with off-track HSL were treated with both ABR and remplissage (20 females, 10 males; mean age = 27.5 ± 5.3 years). One year after surgical treatment, the joint range of motion of the patients was determined by a universal goniometer, and functional status was evaluated using the Rowe score. Results: Sixty shoulders of 60 patients were evaluated over an average period of 1 year. There was no difference between groups regarding age (P = .767) and gender (P = .779). There were 42 female and 18 male patients, with a mean age = 27.5 ± 5.8 years. There was a significant difference between the groups in patients’ external rotation with arm adduction (ER1) (P = .001), external rotation with arm abduction (ER2) (P = .001), forward flexion (P = .001), and abduction (P = .001) measurements between the groups (P < .05). No significant difference was found in internal rotation and Rowe scores between the groups (P= .057, P = .069). A greater improvement was seen in the Rowe score of the ABR + remplissage group (85.2 ± 8.8). No recurrence or complications were observed in any of the patients. Conclusion: The combined procedure of ABR with remplissage may limit joint mobility in patients with anterior shoulder instability. However, it provides satisfactory functional results, with patients in the ABR + remplissage group showing better overall outcomes. Level of Evidence: Level III, Therapeutic study.
