Salas, A.; Ponnusamy, S.; Senkal, C.E.; Meyers-Needham, M.; Selvam, S.P.; Saddoughi, S.A.; Apohan, E.; Sentelle, R.D.; Smith, C.; Gault, C.R.; Obeid, L.M.; El-Shewy, H.M.; Oaks, J.; Santhanam, R.; Marcucci, G.; Baran, Y.; Mahajan, S.; Fernandes, D.; Stuart, R.; Perrotti, D.; Ogretmen, B.
(2011)
The mechanisms by which sphingosine kinase-1 (SK-1)/sphingosine 1-phosphate (S1P) activation contributes to imatinib resistance in chronic myeloid leukemia (CML) are unknown. We show herein that increased SK-1/S1P enhances ...