Kalp ve Damar Cerrahisi Anabilim Dalıhttp://hdl.handle.net/11616/117182024-03-29T14:56:29Z2024-03-29T14:56:29ZRandomized controlled trial of monopolar cautery versus clips for staple line bleeding control in Roux-en-Y gastric bypassGündoğan, ErsinKayaalp, CüneytAktaş, AydınSağlam, KutaySansal, MüfitUylas, UfukGökler, CihanÇiçek, EgemenSümer, Fatihhttp://hdl.handle.net/11616/129242019-07-26T00:02:19Z2018-01-01T00:00:00ZRandomized controlled trial of monopolar cautery versus clips for staple line bleeding control in Roux-en-Y gastric bypass
Gündoğan, Ersin; Kayaalp, Cüneyt; Aktaş, Aydın; Sağlam, Kutay; Sansal, Müfit; Uylas, Ufuk; Gökler, Cihan; Çiçek, Egemen; Sümer, Fatih
Background: Bleeding from the staple line is a rare but serious problem following bariatric surgery. Staple line bleeding control (SLBC) can be achieved in different ways such as the application of sutures, clips, glue or buttressing materials over the staple line. Cauterization alone is generally not preferred due to concerns about debilitating the staple line.
Objectives: The aim of this study was to compare the clip and monopolar cauterization methods for SLBC in laparoscopic Roux-en-Y gastric bypass.
Setting: University hospital.
Methods: A total of 70 morbidly obese patients were randomized into two groups. Patients with previous upper gastrointestinal surgery, re-do procedures and open surgeries were excluded. Their demographic characteristics, intraoperative and postoperative outcomes were examined.
Results: A total of 489 SLBC interventions (274 clips and 215 cauterizations) were performed after 280 stapling applications. SLBC intervention number and location, additional trocar requirement, blood loss and operation time were not different between the groups. In the clip group, two patients required monopolar cauterization when clipping failed. No intraabdominal bleeding or gastrointestinal leakage was seen in any group. Postoperative gastrointestinal hemorrhage was seen in three patients, two in the clip group and one in the cautery group. There was no difference between the groups in terms of postoperative pain score, abdominal drainage amount, hemoglobin level alteration, morbidity or length of stay.
Conclusions: In laparoscopic Roux-en-Y gastric bypass, monopolar cauterization for SLBC can be used instead of clipping. It appears that monopolar cautery is a safe and effective approach for SLBC in laparoscopic Roux-en-Y gastric bypass.
2018-01-01T00:00:00ZRight axilloaxillary cannulation for surgical management of a giant ascending aortic aneurysmBattaloğlu, BektaşAkça, BarışErdil, NevzatÇolak, Cengizhttp://hdl.handle.net/11616/129182019-07-25T00:02:35Z2018-01-01T00:00:00ZRight axilloaxillary cannulation for surgical management of a giant ascending aortic aneurysm
Battaloğlu, Bektaş; Akça, Barış; Erdil, Nevzat; Çolak, Cengiz
2018-01-01T00:00:00ZIs there any difference in risk factors between male and female patients in new-onset atrialfibrillation after coronary artery bypass grafting?Akca, BarisErdil, NevzatColak, Mehmet CengizDisli, Olcay MuratBattaloglu, BektasColak, Cemilhttp://hdl.handle.net/11616/126182019-07-16T07:40:35Z2018-01-01T00:00:00ZIs there any difference in risk factors between male and female patients in new-onset atrialfibrillation after coronary artery bypass grafting?
Akca, Baris; Erdil, Nevzat; Colak, Mehmet Cengiz; Disli, Olcay Murat; Battaloglu, Bektas; Colak, Cemil
Background We aimed to investigate the risk factors of post-coronary artery bypass grafting (CABG) atrial fibrillation (AF) in male and female patients without any history of AF, to identify the sex-specific risk factors, and to examine the effect of sex-specific risk factors on the overall population.
Methods This retrospective study was conducted using the hospital database with 4,758 patients who underwent CABG surgery. Among them, 2,836 patients with complete data participated in this study. The female patients were divided into two groups as patients who developed new-onset AF after CABG and those who did not. The relationship between the patients' variables and risk factors of post-CABG AF was examined.
Results The overall incidence of post CABG AF was 12.9% (386/2,836). Sex-specific incidence of AF was similar: 3.2% (91/690) and 12.9% (277/2146) in female and male patients, respectively (p = 0.849). Multiple analysis revealed the independent risk factors for male and female patients, respectively: mean age (odds ratio [OR] = 1.057, OR = 1,076), age over 65 years (OR = 2.156, OR = 2.736), the European System For Cardiac Operative Risk Evaluation Scores (EuroSCORE) (OR = 1.13, OR = 1.218), COPD (OR = 1.589, OR = 1.789), BUN level (OR = 1.026, OR = 1.019), mean cardiopulmonary bypass (CPB) time (OR = 1.007, OR = 1.010), prolonged CPB time (OR = 1.604, OR = 2.309), mean cross-clamp time (OR = 1.009, OR = 1.017), need of inotropic support (OR = 2.249, OR = 2.731), and mean mechanical ventilation time (VT) (OR = 1.026, OR = 1.027).
Low left ventricular ejection fraction (LVEF) (OR = 1.419), left ventricular (LV) aneurysm repair (OR = 1.533), carotid artery disease (OR = 1.750), prolonged VT (OR = 1.729), and use of intra-aortic balloon pump (IABP) (OR = 2.436) were found to be the risk factors only for male AF patients.
Unstable angina (OR = 1.969), right coronary artery (RCA) disease (OR = 2), prolonged cross-clamp time (OR = 2.152), and the number of grafts per operation (OR = 1.298) were found to be the risk factors only for female AF patients.
Conclusion This study suggests that predictors of AF in the overall population may be due to isolated patient groups. Multiple regression analysis and artificial intelligence modelling should be performed on large-scale, isolated groups to make strong AF prediction.
2018-01-01T00:00:00ZProtective effect of resveratrol against renal oxidative stress in cholestasiAra, CengizKarabulut, Aysun BayÇoban, SacidUğraş, Murat YahyaKırımlıoğlu, VedatYılmaz, Sezaihttp://hdl.handle.net/11616/80692019-11-01T13:23:36Z2005-01-01T00:00:00ZProtective effect of resveratrol against renal oxidative stress in cholestasi
Ara, Cengiz; Karabulut, Aysun Bay; Çoban, Sacid; Uğraş, Murat Yahya; Kırımlıoğlu, Vedat; Yılmaz, Sezai
BACKGROUND/AIMS:
This experimental study was designed to evaluate histological changes of the kidney and renal tissue levels of malondialdehyde (MDA), reduced glutathione (GSH), and nitric oxide (NO) and the effect of resveratrol on these metabolites after bile duct ligation in rats.
METHODS:
Secondary biliary cirrhosis was induced by bile duct ligation for 28 days. Swiss albino rats were divided into three groups. Group 1: Sham (n=7), Group 2: Bile duct ligation (n=7), Group 3: Bile duct ligation plus resveratrol (n=7). Bile duct ligation (BDL) plus resveratrol group received 10 mgr/kg dose of resveratrol intraperitoneally daily throughout 28 days. Kidney tissues were harvested to determine the tissue levels of MDA, GSH, and NO activity. Liver and kidney tissues were removed for light microscopic evaluation.
RESULTS:
Cholestasis was determined by biochemical and pathologic examination. In the resveratrol-treated rats, levels of MDA were significantly lower than those of the BDL group (p < 0.04). The levels of GSH in the resveratrol-treated rats were significantly higher than those in the BDL group (p < 0.01). The levels of NO in the resveratrol group were significantly lower than those in the BDL group (p < 0.01).
CONCLUSION:
The present study demonstrates that intraperitoneal administration of resveratrol in bile duct ligated rats maintains antioxidant defenses and reduces kidney oxidative damage. This effect of resveratrol may be useful in the preservation of renal oxidative stress in cholestasis.
Ren Fail. 2005;27(4):435-40.
2005-01-01T00:00:00Z