TIP, Psikiyatri Anabilim Dalı, Makale Koleksiyonu
http://hdl.handle.net/11616/11822
2024-03-28T18:04:57Z
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Relationship between childhood trauma and suicide probability in obsessive-compulsive disorder
http://hdl.handle.net/11616/12882
Relationship between childhood trauma and suicide probability in obsessive-compulsive disorder
Erbay Gönenir, Lale
The aim of this study is to assess the relationship between childhood trauma with the probability of suicide in obsessive compulsive disorders. Sixty-seven patients who were diagnosed with OCD were included in the study out of the patients who were admitted to Malatya Training and Research Hospital psychiatry outpatient clinic. The research data were collected using Yale Brawn Obsessive Compulsive Scale (YBOCS), Beck Depression (BDS) and Beck Anxiety Scales (BAS), Childhood Trauma Questionnaire-28 (CTQ-28), and Suicide Probability Scale (SPS). CTQ was detected as 35 in 36 of 67 patients who were included in the study. Aggression (p = 0.003), sexual (p = 0.007) and religious (p = 0.023) obsessions and rituelistic (p = 0.000) compulsions were significantly higher in the group with CTQ >= 35. Mild correlation was detected between the SPS score and the scores of CTQ. Correlation remained even when the effect of BAS and BDS scores were excluded. At the end of our study, childhood traumas were found to be associated with obsessive symptoms. In the group with childhood trauma, increased suicide probability was detected independently from depression and anxiety.
2018-01-01T00:00:00Z
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Toxoplasma gondii - obsessive -compulsive disorder relationship: is itdifferent in children?
http://hdl.handle.net/11616/12871
Toxoplasma gondii - obsessive -compulsive disorder relationship: is itdifferent in children?
Miman, Ozlem; Ozcan, Ozlem; Unal, Sueheyla; Atambay, Metin
Background and aim: Obsessive-compulsive disorder (OCD) is a common neuropsychiatric illness. Although the etiology of OCD is still unknown, recent investigations have associated development of OCD with infectious illness. Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes infection of the central nervous system. In the last decade, a lot of researches have focused on the possible relationship between exposure to T. gondii and neuropsychiatric disorders such as schizophrenia. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD in children and adolescents.Methods: We selected 55 patients with OCD (aged between 7 and 16 years) and 59 healthy children and adolescents (aged between 7 and 16 years), and investigated the seropositivity rate for anti-Toxoplasma IgG antibodies by enzyme-linked immunosorbent assay.Results: The seropositivity rate for anti-T. gondii IgG antibodies among OCD patients (21.82%) was found to be higher than the rate in control group (15.25%). However, the difference between the OCD group and the control group was not statistically significant (p>.05).Conclusion: In contrast to studies in adult patients, the results of this study do not support the relationship between T. gondii and OCD children and adolescents.
2018-01-01T00:00:00Z
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Predictors of Turkish University students’ marital attitudes
http://hdl.handle.net/11616/12848
Predictors of Turkish University students’ marital attitudes
Atlı, A
In Turkey, it has been observed that marital attitudes have changed in recent years. In this study, it is aimed to examine the relationship between university students’ marital attitudes and mate selection strategies, gender roles, sex, relationship status and age variables. The sample of the study is made up of 706 (412 females, 294 males) university students. As the data collection instruments, İnönü Marital Attitude Scale, Mate Selection Strategies Inventory and Bem Sex Role Inventory were used in the study. The data analysis was performed using hierarchical regression technique. According to the study findings, virginity and physical attributes mate selection strategies, feminine gender role, age, sex and relationship status variables are significant predictors of university students’ marital attitudes. It was found that importance given to physical attributes and virginity were associated with more positive attitudes towards marriage. Having a higher level of feminine characteristics was associated with more positive attitudes towards marriage.
2018-01-01T00:00:00Z
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Serum ıl-1, ıl-2, ıl-4, ıl-6, ıl-10, tnf-α, and ıfn-γ levels in drug-free, comorbidity-free obsessive-compulsive disorder patients(article) [ilaç kullanmayan ve komorbiditesi olmayan obsesif kompulsif bozukluk hastalarında serum ıl-1, ıl-2, ıl-4, ıl-6, ıl-10, tnf-α ve ıfn-γ düzeyleri]
http://hdl.handle.net/11616/12799
Serum ıl-1, ıl-2, ıl-4, ıl-6, ıl-10, tnf-α, and ıfn-γ levels in drug-free, comorbidity-free obsessive-compulsive disorder patients(article) [ilaç kullanmayan ve komorbiditesi olmayan obsesif kompulsif bozukluk hastalarında serum ıl-1, ıl-2, ıl-4, ıl-6, ıl-10, tnf-α ve ıfn-γ düzeyleri]
Gönenir Erbay, L.; Akti Kavuran, N.; Taşkapan, Ç.; İnce, L.U.; Yoloğlu, S.; Temelli, H.G.; Ünal, S.
Objective: Increasing evidence suggests that certain inflammatory factors, especially cytokines, can lead to neurochemical and behavioural changes via their role in the brain signalling system. Studies investigating cytokine abnormalities in obsessive-compulsive disorder (OCD) have yielded conflicting results thus far. The aim of this study was to investigate the serum IL-1, IL-4, IL-6, IL-10, TNF-α, and IFN-γ levels in drug-free, comorbidity-free patients with OCD. Methods: Forty comorbidity-free, drug-free OCD patients and 40 age- and sex-matched healthy volunteers were included in the study. Clinical severity was assessed using the Yale-Brown Obsessive-Compulsive Evaluation Scale (YBOCES). Results: IL-1 levels were significantly higher and IL-2, IL-6, and TNF-α levels were significantly lower in patients than in controls. No differences were observed in IL-4, IL-10, and IFN-γ levels. How-ever, a negative relationship was found between IL-1 levels and compulsive symptoms (YBOCES) in OCD patients. Conclusions: Our findings suggest the possible role of cytokines in the pathogenesis of OCD. It is important to continue investigating the role of cytokines and other immunological markers in both the etiology and treatment of OCD. © 2018, Cukurova University, Faculty of Medicine. All rights resreved.
2018-01-01T00:00:00Z