• Comparison of Dissolution Profiles of Commercially Available Lamivudine Tablets 

  Ozturk, Naile; Kaynak, Mustafa Sinan; Sahin, Selma (Dıssolutıon technologıes, ınc, 9 yorkrıdge traıl, hockessın, de 19707-9633 usa, 2015)

  The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ...
• In Vitro PDGF-B Gene Silencing Studies and In Vivo Delivery of siRNA to the Rat Kidney Using Chitosan/siRNA Nanoplexes 

  Salva, Emine; Ozbas Turan, Suna; Alan, Saadet; Akbuga, Julide (Marmara unıv, fac medıcıne, haydarpasa, ıstan, 34668, turkey, 2016)

  The targeting of specific genes responsible from onset and progression of kidney diseases offer a new therapeutic strategy in the field of renal gene therapy. The altered expression of platelet derived growth factor (PDGF) ...
• Evaluation of Pharmaceutical Quality of Conventional Dosage Forms Containing Paracetamol and Caffeine Available in the Turkish Drug Market 

  Akgeyik, Emrah; Kaynak, Mustafa Sinan; Celebier, Mustafa; Altinoz, Sacide; Sahin, Selma (Dıssolutıon technologıes, ınc, 9 yorkrıdge traıl, hockessın, de 19707-9633 usa, 2016)

  The aim of this study was to evaluate the quality of conventional paracetamol- (PA) and caffeine- (CA) containing combined dosage forms in the Turkish drug market. For this purpose, weight variation, content uniformity, ...
• Anti-inflammatory Montelukast prevents toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin: Oxidative stress, histological alterations in liver, and serum cytokine levels 

  Bentli, Recep; Ciftci, Osman; Cetin, Asli; Otlu, Ali (Sage publıcatıons ınc, 2455 teller rd, thousand oaks, ca 91320 usa, 2016)

  This study aimed to investigate the potential beneficial effects of the montelukast (ML) on oxidative stress and histological alterations in liver tissues and cytokine levels in rats intoxicated with 2,3,7,8-tetrachlorod ...
• Generation of stable cell line by using chitosan as gene delivery system 

  Salva, Emine; Turan, Suna Ozbas; Ekentok, Ceyda; Akbuga, Julide (Sprınger, van godewıjckstraat 30, 3311 gz dordrecht, netherlands, 2016)

  Establishing stable cell lines are useful tools to study the function of various genes and silence or induce the expression of a gene of interest. Nonviral gene transfer is generally preferred to generate stable cell lines ...
• Tocilizumab's effect on cognitive deficits induced by intracerebroventricular administration of streptozotocin in Alzheimer's model 

  Elcioglu, H. Kubra; Aslan, Ersin; Ahmad, Sarfraz; Alan, Saadet; Salva, Emine; Elcioglu, O. Haluk; Kabasakal, Levent (Sprınger, van godewıjckstraat 30, 3311 gz dordrecht, netherlands, 2016)

  Neuroinflammation plays pivotal roles in the pathogenesis of Alzheimer's disease (AD). IL-6 is pleiotropic cytokine which plays significant pathological role in inflammatory diseases and causes prolonged inflammation. ...
• A Guidance Manual for the Toxicity Assessment of Traditional Herbal Medicines 

  Aydin, Ahmet; Aktay, Goknur; Yesilada, Erdem (Natural products ınc, 7963 anderson park ln, westervılle, oh 43081 usa, 2016)

  Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, ...
• The investigation of effects to cell proliferation and adsorption of new ternary and binary scaffolds 

  Sirkeci, A; Salva, E; Turan, SO; Akbuga, J (Mary ann lıebert, ınc, 140 huguenot street, 3rd fl, new rochelle, ny 10801 usa, 2016)
• The silencing of PDGF-B pathway by Chitosan/siRNA nanoplexes in therapy of the experimental mesangial proliferative glomerulonephritis 

  Salva, E.; Alan, S.; Yilmaz, I.; Turan, S. O.; Akbuga, J. (Mary ann lıebert, ınc, 140 huguenot street, 3rd fl, new rochelle, ny 10801 usa, 2016)
• Comparison of short and long siVEGF/encapsulating chitosan nanoparticles in breast cancer cell lines 

  Comez, B.; Akbuga, J.; Salva, E. (Mary ann lıebert, ınc, 140 huguenot street, 3rd fl, new rochelle, ny 10801 usa, 2016)
• New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA(A)R affinity according to molecular modeling studies 

  Sari, Suat; Karakurt, Arzu; Uslu, Harun; Kaynak, F. Betul; Calis, Unsal; Dalkara, Sevim (Elsevıer france-edıtıons scıentıfıques medıcales elsevıer, 65 rue camılle desmoulıns, cs50083, 92442 ıssy-les-moulıneaux, france, 2016)

  (Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent anticonvulsant activities have been reported so far, however ...
• The effects of chitosan/miR-200c nanoplexes on different stages of cancers in breast cancer cell lines 

  Kaban, Kubra; Salva, Emine; Akbuga, Julide (Elsevıer scıence bv, po box 211, 1000 ae amsterdam, netherlands, 2016)

  Dysregulation of miR-200c in breast cancer has been associated with migration, epithelial mesenchymal transition (EMT), angiogenesis and metastasis of the tumor cells. Therefore, the modulation of miR-200c offers a promising ...
• The Effects to GM-CSF Expression and Fibroblast Proliferation of pGM-CSF Containing Chitosan/PVP Hydrogels 

  Salva, Emine; Akbuga, Julide (Marmara unıv, fac pharmacy, haydarpasa, ıstanbul, 34668, turkey, 2017)

  The aim of this study was to develop pGM-CSF containing chitosan/PVP hydrogel system for gene delivery. The hydrogels in semi-interpenetrating polymer network (semi-IPN) structure were synthesized by glutaraldehyde ...
• The enhancement of gene silencing efficiency with chitosan-coated liposome formulations of siRNAs targeting HIF-1 alpha and VEGF (vol 478, pg 147, 2015) 

  Salva, Emine; Turan, Suna Ozbas; Eren, Fatih; Akbuga, Julide (Elsevıer scıence bv, po box 211, 1000 ae amsterdam, netherlands, 2017)
• Syntheses of 1,2,3-triazole-bridged pyranose sugars with purine and pyrimidine nucleobases and evaluation of their anticancer potential 

  Halay, Erkan; Ay, Emriye; Salva, Emine; Ay, Kadir; Karayildirim, Tamer (Taylor & francıs ınc, 530 walnut street, ste 850, phıladelphıa, pa 19106 usa, 2017)

  With the aim to create a library of compounds with potential bioactivities by combining special characteristics of two important groups such as nucleobases and carbohydrates, twenty 1,4-disubstituted-triazole nucleosides ...
• In Vitro Dose Studies on Chitosan Nanoplexes for microRNA Delivery in Breast Cancer Cells 

  Kaban, Kubra; Salva, Emine; Akbuga, Julide (Mary ann lıebert, ınc, 140 huguenot street, 3rd fl, new rochelle, ny 10801 usa, 2017)

  Changes in microRNA (miRNA) expression levels that play important roles in regulation lead to many pathological events such as cancer. The miR-200 family is an important target in cancer therapy. The aim of this study is ...
• Inhibition of Glomerular Mesangial Cell Proliferation by siPDGF-B- and siPDGFR-beta-Containing Chitosan Nanoplexes 

  Salva, Emine; Turan, Suna Ozbas; Akbuga, Julide (Sprınger, 233 sprıng st, new york, ny 10013 usa, 2017)

  Mesangioproliferative glomerulonephritis is a disease that has a high incidence in humans. In this disease, the proliferation of glomerular mesangial cells and the production of extracellular matrix are important. In recent ...
• Evaluation of Antitumor Activity of a Non-Steroidal Anti-Inflammatory Drug, Ibuprofen, by a Targeted Nanoparticulate System 

  Ozturk, Naile; Kara, Asli; Vural, Imran (Colegıo farmaceutıcos provıncıa de buenos aıres, dept cıentıfıco, calle 5 no 966, la plata, 00000, argentına, 2017)

  In this study we aimed to develop a new targeted nanoparticulate system to obtain site specific delivery of ibuprofen and to determine its antitumor efficiency. The potential effect of ibuprofen as an antitumor agent was ...
• Development of hplc methods for ındividual determination of 20 active pharmaceutical ıngredientsfor ussing-chamber studies 

  Kaynak, Mustafa Sinan; Akgeyik, Emrah; Ates, Muge; Celebier, Mustafa; Sahin, Selma (Bentham scıence publ ltd, executıve ste y-2, po box 7917, saıf zone, 1200 br sharjah, u arab emırates, 2017)

  Background: The aim of this study was to develop HPLC methods for individual determination of 20 active pharmaceutical ingredients (amoxicillin sodium, antipyrine, atenolol, caffeine, carbamazepine, cimetidine, enalapril, ...
• Beta-cryptoxanthin ameliorates metabolic risk factors by regulating nf-kappa b and nrf2 pathwaysin insulin resistance induced by high-fat diet in rodents 

  Akdemir, Fatih; Yilmaz, Ismet; Sahin, Nurhan (Pergamon-elsevıer scıence ltd, the boulevard, langford lane, kıdlıngton, oxford ox5 1gb, england, 2017)

  The aim of this experiment was to determine the effects of beta-cryptoxanthin (BCX) on the cardiometabolic health risk factors and NF-kappa B and Nrf2 pathway in insulin resistance induced by high-fat diet (HFD) in rodents. ...

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