Ozturk, Naile; Kaynak, Mustafa Sinan; Sahin, Selma(Dıssolutıon technologıes, ınc, 9 yorkrıdge traıl, hockessın, de 19707-9633 usa, 2015)
The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ...
The targeting of specific genes responsible from onset and progression of kidney diseases offer a new therapeutic strategy in the field of renal gene therapy. The altered expression of platelet derived growth factor (PDGF) ...
Akgeyik, Emrah; Kaynak, Mustafa Sinan; Celebier, Mustafa; Altinoz, Sacide; Sahin, Selma(Dıssolutıon technologıes, ınc, 9 yorkrıdge traıl, hockessın, de 19707-9633 usa, 2016)
The aim of this study was to evaluate the quality of conventional paracetamol- (PA) and caffeine- (CA) containing combined dosage forms in the Turkish drug market. For this purpose, weight variation, content uniformity, ...
Bentli, Recep; Ciftci, Osman; Cetin, Asli; Otlu, Ali(Sage publıcatıons ınc, 2455 teller rd, thousand oaks, ca 91320 usa, 2016)
This study aimed to investigate the potential beneficial effects of the montelukast (ML) on oxidative stress and histological alterations in liver tissues and cytokine levels in rats intoxicated with 2,3,7,8-tetrachlorod ...
Establishing stable cell lines are useful tools to study the function of various genes and silence or induce the expression of a gene of interest. Nonviral gene transfer is generally preferred to generate stable cell lines ...
Elcioglu, H. Kubra; Aslan, Ersin; Ahmad, Sarfraz; Alan, Saadet; Salva, Emine; Elcioglu, O. Haluk; Kabasakal, Levent(Sprınger, van godewıjckstraat 30, 3311 gz dordrecht, netherlands, 2016)
Neuroinflammation plays pivotal roles in the pathogenesis of Alzheimer's disease (AD). IL-6 is pleiotropic cytokine which plays significant pathological role in inflammatory diseases and causes prolonged inflammation. ...
Aydin, Ahmet; Aktay, Goknur; Yesilada, Erdem(Natural products ınc, 7963 anderson park ln, westervılle, oh 43081 usa, 2016)
Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, ...
Sari, Suat; Karakurt, Arzu; Uslu, Harun; Kaynak, F. Betul; Calis, Unsal; Dalkara, Sevim(Elsevıer france-edıtıons scıentıfıques medıcales elsevıer, 65 rue camılle desmoulıns, cs50083, 92442 ıssy-les-moulıneaux, france, 2016)
(Arylalkyl)azoles (AAAs) emerged as a novel class of antiepileptic agents with the invention of nafimidone and denzimol. Several AAA derivatives with potent anticonvulsant activities have been reported so far, however ...
Dysregulation of miR-200c in breast cancer has been associated with migration, epithelial mesenchymal transition (EMT), angiogenesis and metastasis of the tumor cells. Therefore, the modulation of miR-200c offers a promising ...
The aim of this study was to develop pGM-CSF containing chitosan/PVP hydrogel system for gene delivery. The hydrogels in semi-interpenetrating polymer network (semi-IPN) structure were synthesized by glutaraldehyde ...
With the aim to create a library of compounds with potential bioactivities by combining special characteristics of two important groups such as nucleobases and carbohydrates, twenty 1,4-disubstituted-triazole nucleosides ...
Kaban, Kubra; Salva, Emine; Akbuga, Julide(Mary ann lıebert, ınc, 140 huguenot street, 3rd fl, new rochelle, ny 10801 usa, 2017)
Changes in microRNA (miRNA) expression levels that play important roles in regulation lead to many pathological events such as cancer. The miR-200 family is an important target in cancer therapy. The aim of this study is ...
Salva, Emine; Turan, Suna Ozbas; Akbuga, Julide(Sprınger, 233 sprıng st, new york, ny 10013 usa, 2017)
Mesangioproliferative glomerulonephritis is a disease that has a high incidence in humans. In this disease, the proliferation of glomerular mesangial cells and the production of extracellular matrix are important. In recent ...
Ozturk, Naile; Kara, Asli; Vural, Imran(Colegıo farmaceutıcos provıncıa de buenos aıres, dept cıentıfıco, calle 5 no 966, la plata, 00000, argentına, 2017)
In this study we aimed to develop a new targeted nanoparticulate system to obtain site specific delivery of ibuprofen and to determine its antitumor efficiency. The potential effect of ibuprofen as an antitumor agent was ...
Kaynak, Mustafa Sinan; Akgeyik, Emrah; Ates, Muge; Celebier, Mustafa; Sahin, Selma(Bentham scıence publ ltd, executıve ste y-2, po box 7917, saıf zone, 1200 br sharjah, u arab emırates, 2017)
Background: The aim of this study was to develop HPLC methods for individual determination of 20 active pharmaceutical ingredients (amoxicillin sodium, antipyrine, atenolol, caffeine, carbamazepine, cimetidine, enalapril, ...
The aim of this experiment was to determine the effects of beta-cryptoxanthin (BCX) on the cardiometabolic health risk factors and NF-kappa B and Nrf2 pathway in insulin resistance induced by high-fat diet (HFD) in rodents. ...