Browsing Temel Tıp Bilimleri by Author "Merrill, Gary F."

Now showing items 1-3 of 3

Replication independent MCB gene induction and deoxyribonucleotide accumulation at G1 S in Saccharomyces cerevisiae

Koç, Ahmet; Wheeler, Linda J.; Mathews, Christopher K.; Merrill, Gary F. (J Biol Chem, 2003)

In Saccharomyces cerevisiae, many genes encoding enzymes involved in deoxyribonucleotide synthesis are expressed preferentially near the G1/S boundary of the cell cycle. The relationship between the induction ...
Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase

Koç, Ahmet; Mathews, Christopher K.; Wheeler, Linda J.; Gross, Michael K.; Merrill, Gary F. (J Biol Chem, 2006)

Thioredoxin was initially identified by its ability to serve as an electron donor for ribonucleotide reductase in vitro. Whether it serves a similar function in vivo is unclear. In Saccharomyces cerevisiae, it was ...
Checkpoint deficient rad53 11 yeast cannot accumulate dNTPs in response to DNA damage

Koç, Ahmet; Merrill, Gary F. (Biochem Biophys Res Commun., 2007)

Deoxyribonucleotide pools are maintained at levels that support efficient and yet accurate DNA replication and repair. Rad53 is part of a protein kinase regulatory cascade that, conceptually, promotes dNTP accumulation ...

Now showing items 1-3 of 3

Search DSpace