Browsing TIP, Tıbbi Biyoloji ve Genetik Anabilim Dalı, Makale Koleksiyonu by Author "Ünlü, Ercan Selçuk"

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Evidence for the presence of a second electron donor for cytoplasmic thioredoxins in the yeast s cerevisiae

Koç, Ahmet; Karakaya, Hüseyin Çağlar; Ünlü, Ercan Selçuk (T Journal Biol, 2006)

In yeast, the cytoplasmic thioredoxin system is composed of NADPH, thioredoxin reductase-1 (TRR1) and 2 thioredoxin genes (TRX1, TRX2). In this study, using yeast knockout mutants for TRR1, TRX1 and TRX2 genes, the role ...
Effects of deleting mitochondrial Antioxidant genes on life span

Ünlü, Ercan Selçuk; Koç, Ahmet (Ann N Y Acad Sci., 2007)

Reactive oxygen species (ROS) damage biomolecules, accelerate aging, and shorten life span, whereas antioxidant enzymes mitigate these effects. Because mitochondria are a primary site of ROS generation and also a primary ...

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