DSpace Repository

Comparative evaluation of toxicological effects and recovery patterns in zebrafish (danio rerio) afterexposure to phosalone-based and cypermethrin-based pesticides

Show simple item record

dc.contributor.author Korkmaz, Volkan
dc.contributor.author Gungordu, Abbas
dc.contributor.author Ozmen, Murat
dc.date.accessioned 2019-07-09T07:35:02Z
dc.date.available 2019-07-09T07:35:02Z
dc.date.issued 2018
dc.identifier.citation Korkmaz, V. Gungordu, A . (2018). Comparative evaluation of toxicological effects and recovery patterns in zebrafish (danio rerio) afterexposure to phosalone-based and cypermethrin-based pesticides. Cilt:160. 265-272 ss. tr_TR
dc.identifier.uri http://hdl.handle.net/11616/12438
dc.description.abstract This study evaluated the toxic effects and recovery patterns in zebrafish (Danio redo) after exposure to phosalone-based (PBP) and cypermethrin-based (CBP) pesticides. Initially, the 96 h LC50 values of the pesticides were calculated as being 5.35 mu g of active ingredient (AI) L-1 for CBP and 217 mu g AI L-1 for PBP based on measured concentrations. Accordingly, experimental groups were exposed to three sublethal concentrations of pesticides for 96 h, separately, and then zebrafish were transferred to pesticide-free conditions for 10 and 20 days recovery periods. Biochemical markers were assessed including carboxylesterase (CaE), acetylcholinesterase (AChE), glutathione S-transferase (GST), lactate dehydrogenase, glutathione peroxidase, catalase, alanine and aspartate aminotransferase (ALT, AST) activities after the exposure and recovery periods. Also, the pesticide concentrations in test water were quantified by high-performance liquid chromatography (HPLC) analysis. Our results showed that AChE and CaE activities were significantly inhibited and GST was induced by both pesticides after 96 h exposure. For PBP exposure, the decreases for GST induction and CaE inhibition showed a partial recovery in pesticide-free conditions. However, the decreases in AChE activity for CBP exposure and insufficient increases in same enzyme activity for PBP exposure after 20 days in pesticide-free conditions indicated that the projected recovery period was not enough to the recovery of AChE activities and for the improvement of fish health. tr_TR
dc.language.iso eng tr_TR
dc.publisher Academıc press ınc elsevıer scıence, 525 b st, ste 1900, san dıego, ca 92101-4495 usa tr_TR
dc.relation.isversionof 10.1016/j.ecoenv.2018.05.055 tr_TR
dc.rights info:eu-repo/semantics/openAccess tr_TR
dc.subject Oxıdatıve stress tr_TR
dc.subject acetylcholınesterase actıvıty tr_TR
dc.subject ın-vıvo tr_TR
dc.subject fısh tr_TR
dc.subject chlorpyrıfos tr_TR
dc.subject water tr_TR
dc.subject behavıor tr_TR
dc.subject enzymes tr_TR
dc.subject embryos tr_TR
dc.subject larvae tr_TR
dc.title Comparative evaluation of toxicological effects and recovery patterns in zebrafish (danio rerio) afterexposure to phosalone-based and cypermethrin-based pesticides tr_TR
dc.type article tr_TR
dc.relation.journal Ecotoxıcology and envıronmental safety tr_TR
dc.contributor.department İnönü Üniversitesi tr_TR
dc.identifier.volume 160 tr_TR
dc.identifier.issue 0 tr_TR
dc.identifier.startpage 265 tr_TR
dc.identifier.endpage 272 tr_TR


Files in this item

This item appears in the following Collection(s)

Show simple item record