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Quantitative determination of some phenolics in Origanum laevigatum Boiss. extracts via validated LC-MS/MS method and antioxidant activity

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dc.contributor.author Arabacı, Turan
dc.date.accessioned 2019-07-25T06:01:38Z
dc.date.available 2019-07-25T06:01:38Z
dc.date.issued 2018
dc.identifier.citation Arabacı, T. (2018). Quantitative determination of some phenolics in Origanum laevigatum Boiss. extracts via validated LC-MS/MS method and antioxidant activity. Cilt:12 Sayı:2, 121-127 ss. tr_TR
dc.identifier.uri http://hdl.handle.net/11616/12921
dc.description.abstract In this study, quantities of some phenolics; caffeic acid, (E)-ferulic acid, rosmarinic acid, chlorogenic acid, fumaric acid, gallic acid, pyrogallol and vanillin in the directly methanol (M1), chloroform (C), acetone (Ac) and methanol (M2) extratcs obtained from Origanum laevigatum Boiss. from Turkey were investigated via liquid chromatography and tandem mass spectrometry (LC-MS/MS). Curcumin was used as an internal standard. Caffeic acid, chlorogenic acid, rosmarinic acid and gallic acid were determined as the most abundant phenolic acids in the studied extracts using LC-MS/MS. In LC-MS/MS measurements relative standard deviations (RSD %) for caffeic acid, (E)-ferulic acid, rosmarinic acid, chlorogenic acid, fumaric acid, gallic acid, pyrogallol and vanillin were found to be 8.04, 5.21, 5.45, 3.73, 5.44, 4.85, 5.47 and 6.57 % respectively. For the investigated analytes, the correlation coefficient was found in the range of 0.9803 to 0.9981. Furthermore, antioxidant properties of the extracts were determined based on 2,2-diphenyl-1-picrylhydrazyl (DPPH), beta-carotene linoleic acid and cupric (Cu2+) ion reducing power assay (CUPRAC). Acetone (Ac) and methanol (M2) extracts showed high activity in all test assays due to their high concentration of rosmarinic acid, caffeic acid and gallic acid in the extracts. (C) 2018 ACG Publications. All rights reserved. tr_TR
dc.language.iso eng tr_TR
dc.publisher Acg yayınları, yenikent mahallesi, fırat caddesi, 1-3, gebze-kocaeli, 41400, türkiye tr_TR
dc.relation.isversionof 10.25135/jcm.21.18.11.1115 tr_TR
dc.rights info:eu-repo/semantics/openAccess tr_TR
dc.subject Chemıcal-Composıtıon tr_TR
dc.subject Essentıal Oıl tr_TR
dc.subject In-Vıtro tr_TR
dc.subject L. tr_TR
dc.subject Capacıty tr_TR
dc.title Quantitative determination of some phenolics in Origanum laevigatum Boiss. extracts via validated LC-MS/MS method and antioxidant activity tr_TR
dc.type article tr_TR
dc.relation.journal Journal of chemıcal metrology tr_TR
dc.contributor.department İnönü Üniversitesi tr_TR
dc.identifier.volume 12 tr_TR
dc.identifier.issue 2 tr_TR
dc.identifier.startpage 121 tr_TR
dc.identifier.endpage 127 tr_TR


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