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Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease

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dc.contributor.author Acikgoz, Nusret
dc.contributor.author Kurtoglu, Ertugrul
dc.contributor.author Yagmur, Julide
dc.contributor.author Kapicioglu, Yelda
dc.contributor.author Cansel, Mehmet
dc.contributor.author Ermis, Necip
dc.date.accessioned 2019-08-08T06:16:20Z
dc.date.available 2019-08-08T06:16:20Z
dc.date.issued 2017
dc.identifier.citation Acikgoz, N. Kurtoglu, E. Yagmur, J. Kapicioglu, Y. Cansel, M. Ermis, N. (2017). Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease.Cilt:69. Sayı:1. 65-70 ss. tr_TR
dc.identifier.uri http://hdl.handle.net/11616/13302
dc.description.abstract Behcet disease (BD) is a multisystemic disorder characterized by endothelial dysfunction and inflammation. Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress. Sixty patients with BD and 50 control individuals were included to investigate the relationship between MHR and endothelial dysfunction. Endothelial function was assessed by flow- and nitroglycerin-mediated dilatation technique (FMD and NMD, respectively). Serum high-sensitivity C-reactive protein (hsCRP) levels were measured in all study participants. The MHR and hsCRP levels were significantly higher in patients with active BD than in controls. Brachial artery FMD was significantly lower in patients with active BD than in controls. Brachial artery NMD was similar between groups. There was a strong inverse correlation between MHR and FMD and a strong positive correlation between MHR and serum hsCRP levels. Thus, elevated MHR may be a useful marker reflecting impaired endothelial function and systemic inflammation in patients with BD. tr_TR
dc.language.iso eng tr_TR
dc.publisher Sage publıcatıons ınc, 2455 teller rd, thousand oaks, ca 91320 usa tr_TR
dc.relation.isversionof 10.1177/0003319717704748 tr_TR
dc.rights info:eu-repo/semantics/openAccess tr_TR
dc.subject Markers tr_TR
dc.subject hdl tr_TR
dc.subject ınflammatıon tr_TR
dc.subject ınvolvement tr_TR
dc.title Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease tr_TR
dc.type article tr_TR
dc.relation.journal Angıology tr_TR
dc.contributor.department İnönü Üniversitesi tr_TR
dc.identifier.volume 69 tr_TR
dc.identifier.issue 1 tr_TR
dc.identifier.startpage 65 tr_TR
dc.identifier.endpage 70 tr_TR


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