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Browsing Araştırma Çıktıları | Wos by Author "Ucar, M"

Browsing Araştırma Çıktıları | Wos by Author "Ucar, M"

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  • Carbon tetrachloride-induced nephrotoxicity and protective effect of 
    Ozturk, F; Ucar, M; Ozturk, IC; Vardi, N; Batcioglu, K (2003)
    Objectives. To observe the changes in the antioxidative defense enzymes and to detect the alterations of renal microscopy after carbon tetrachloride (CCl4) administration in rats and to investigate the possible protective ...
  • Erdosteine prevents doxorubicin-induced cardiotoxicity in rats 
    Yagmurca, M; Fadillioglu, E; Erdogan, H; Ucar, M; Sogut, S; Irmak, MK (2003)
    The clinical use of doxorubicin (Dxr) is limited by its cardiotoxic effects which are mediated by oxygen radicals. The purpose of this study was to investigate in vivo protective effects of erdosteine, an antioxidant agent ...
  • Protective effects of caffeic acid phenethyl ester on 
    Fadillioglu, E; Oztas, E; Erdogan, H; Yagmurca, M; Sogut, S; Ucar, M; Irmak, MK (2004)
    The prevention of doxorubicin (DXR)-induced cardiotoxicity may be helpful to improve future DXR therapy. The aim of this study was to investigate the cardio-protective effects of caffeic acid phenethyl ester (CAPE), an ...
  • Caffeic acid phenethyl ester as a protective agent against doxorubicin 
    Yagmurca, M; Erdogan, H; Iraz, M; Songur, A; Ucar, M; Fadillioglu, E (2004)
    Background: Nephrotoxicity is one of the important side effects of antracycline antibiotics. The aim of this study was to investigate the effects of caffeic acid phenethyl ester (CAPE), an antioxidant agent, against ...
  • Protective role of caffeic acid phenethyl ester (cape) on 
    Parlakpinar, H; Tasdemir, S; Polat, A; Bay-Karabulut, A; Vardi, N; Ucar, M; Acet, A (2005)
    The toxicity of gentamicin (GEN) in the kidney seems to relate to the generation of reactive oxygen species (ROS). Caffeic acid phenethyl ester (CAPE) has been demonstrated to have antioxidant, free radical scavenger and ...
  • Myocardial ischemia/reperfusion-induced oxidative renal damage in rats: 
    Ozer, MK; Parlakpinar, H; Vardi, N; Cigremis, Y; Ucar, M; Acet, A (2005)
    Myocardial ischemia-reperfusion (MI/R) may induce renal damage. A rat model of M/IR injury was established. The left coronary artery was clamped for 30 min, constituting the ischemic period, and was then released for 120 ...
  • Ischemia-reperfusion leads to depletion of glutathione content and 
    Ozer, MK; Parlakpinar, H; Cigremis, Y; Ucar, M; Vardi, N; Acet, A (2005)
    During restoration of blood flow of the ischemic heart induced by coronary occlusion, free radicals cause lipid peroxidation with myocardial injury. Lipid peroxidation end-products, such as malondialdehyde (MDA), have been ...
  • Protein oxidation and lipid peroxidation after renal 
    Erdogan, H; Fadillioglu, E; Yagmurca, M; Ucar, M; Irmak, MK (2006)
    Oxygen radicals have roles in the renal ischemia-reperfusion (IR) injury usually encountered in several conditions such as renal transplantation. The aim of this study was to investigate the effects of erdosteine and ...
  • Protective role of aminoguanidine on gentamicin-induced acute renal 
    Polat, A; Parlakpinar, H; Tasdemir, S; Colak, C; Vardi, N; Ucar, M; Emre, MH; Acet, A (2006)
    The toxicity of aminoglycosides including gentamicin (GEN), the most widely used drug in this category, is believed to be related to the generation of reactive oxygen species (ROS) in the kidney. Aminoguanidine (AG) is ...
  • Protective effects of caffeic acid phenethyl ester (CAPE) on 
    Parlakpinar, H; Ozer, MK; Ucar, M; Gaffaroglu, M; Vardi, N; Koc, M; Acet, A (2006)
    Amikacin (AK) has nephrotoxic side effects. AK-induced nephrotoxicity may be the consequence of oxidative stress and so anti-oxidant agents could be useful in reducing AK toxicity. Caffeic acid phenethyl ester (CAPE) was ...
  • Protective effect of chelerythrine on gentamicin-induced nephrotoxicity 
    Parlakpinar, H; Tasdemir, S; Polat, A; Bay-Karabulut, A; Vardi, N; Ucar, M; Yanilmaz, M; Kavakli, A; Acet, A (2006)
    Despite their beneficial effects, aminoglycosides including gentamicin (GEN) have considerable nephrotoxic side-effects. The toxicity of GEN at the level of the kidney seems to relate to the generation of reactive oxygen ...
  • The Effects of Nitric Oxide on Rat Stomach Injury Induced by 
    Yagmurca, M; Ucar, M; Fadillioglu, E; Erdogan, H; Ozturk, F (2009)
    Aim: Acetylsalicylic acid (ASA, aspirin), which is one of the most frequently used drugs in the world. causes severe gastric mucosal injury. Nitric oxide (NO) is synthesized from L-arginine by nitric oxide synthase (NOS). ...
  • Approach to Acute Iron Intoxication: A Case Report 
    Ozgul, U; Erdogan, MA; Gedik, E; Ucar, M; Aydogan, MS; Togal, T (2011)
    In adults, the main causes of iron poisoning are intake suicide attempts and an overdose of iron during pregnancy. The severity of intoxication depends on the amount of iron. When serum iron level exceeds the iron binding ...
  • Bispectral Index Monitoring to Guide End-Tidal Isoflurane Concentration 
    Toprak, HI; Sener, A; Gedik, E; Ucar, M; Karahan, K; Aydogan, MS; Ersoy, MO (2011)
    It has been shown that anesthetic requirements during liver transplantation are inversely proportional to the degree of hepatic dysfunction. We investigate alterations during the three phases of requirements for intraoperative ...
  • Comparison of Antioxidant Effects of Isoflurane and Propofol in Patient 
    Ucar, M; Ozgul, U; Polat, A; Toprak, HI; Erdogan, MA; Aydogan, MS; Durmus, M; Ersoy, MO (2012)
  • Effects of propofol and dexmedetomidine on motor coordination and 
    Yucel, A; Aydogan, MS; Parlakpinar, H; Erdogan, MA; Kurt, A; Ucar, M; Durmus, M (2012)
    Objective: The objective of this study was to compare the effects of two drugs on motor performance and analgesic efficacy in a rat model. Material and methods: Rats were randomly divided into four groups as follows: ...
  • Effects of beta- Glucan Liver Ischemia/Reperfusion Injury in Rats 
    Aydogan, MS; Yucel, A; Erdogan, MA; Polat, A; Cetin, A; Ucar, M; Duran, ZR; Durmus, M (2012)
  • Effects of Oral beta- Glucan on Liver Ischemia/Reperfusion Injury in 
    Aydogan, MS; Yucel, A; Erdogan, MA; Polat, A; Cetin, A; Ucar, M; Duran, ZR; Colak, C; Durmus, M (2013)
    Aim. Ischemia/reperfusion (IR) injury (IRI) in liver transplant patients may negatively affect graft function. Although beta-glucan protects kidneys against IRI, its effect on the liver is unknown. This study sought to ...
  • Effects of Isoflurane and Propofol on Hepatic and Renal Functions and 
    Ozgul, U; Ucar, M; Erdogan, MA; Aydogan, MS; Toprak, HI; Colak, C; Durmus, M; Ersoy, MO (2013)
    We compared postoperative hepatic and renal functions and coagulation profiles in living donors undergoing right hepatectomy under isofiurane (n = 40) versus propofol (n = 40) anesthesia. After induction, anesthesia was ...
  • Trending and Accuracy of Noninvasive Hemoglobin Monitoring During Liver 
    Toprak, H; Ucar, M; Colak, Y; Ucar, H (2015)