dc.contributor.author |
Aydin, C |
|
dc.contributor.author |
Otan, E |
|
dc.contributor.author |
Akbulut, S |
|
dc.contributor.author |
Karakas, S |
|
dc.contributor.author |
Kayaalp, C |
|
dc.contributor.author |
Karagul, S |
|
dc.contributor.author |
Colak, C |
|
dc.contributor.author |
Gonultas, F |
|
dc.contributor.author |
Yilmaz, S |
|
dc.date.accessioned |
2022-03-30T13:21:48Z |
|
dc.date.available |
2022-03-30T13:21:48Z |
|
dc.date.issued |
2015 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/59725 |
|
dc.description.abstract |
Background. The aim of this study was to identify the risk factors related to mortality in liver transplant (LT) patients with post-transplantation pulmonary complications. |
|
dc.description.abstract |
Method. Patients who underwent liver transplantation in our clinic between January 2010 and January 2012 were retrospectively reviewed for post-transplantation pulmonary complications. Demographic, clinical, radiologic, and postoperative chart data of 153 patients with pulmonary complications were analyzed using an independent samples Student t test, Pearson's chi(2) test, Fisher's exact test, and Yate's corrected chi(2) test. Mortality was analyzed using a multiple logistic regression model. The best-fit breakpoint resulting in a cut-off value for the variables of interest was determined using ROC curves and the Youden index. |
|
dc.description.abstract |
Results. The 153 patients with pulmonary complication were divided into 2 groups: mortality (n = 53) and survival (n = 100). Univariate analyses showed significant differences between these 2 groups with respect to MELD score (P = .035), duration of mechanical ventilation (P>.001), pneumonia (P = .01), and endotracheal culture results (P = .001). In the multivariate analysis, hemoglobin (P = .03, odds ratio [OR]: 1.239), MELD score (P = .027, OR: 1.064), duration of mechanical ventilation (P = .003, OR: 1.091), and age (P = .042, OR: 1.001) were significant risk factors for mortality. The best-fit breakpoint analysis yielded cut-off values for hemoglobin (>11.2, sensitivity: 50.9%, specificity: 70%), MELD score (>16, sensitivity: 73.6%, specificity: 42%) and duration of mechanical ventilation (>3, sensitivity: 62.3%, specificity: 76%). |
|
dc.description.abstract |
Conclusion. Advanced age, high hemoglobin level, high MELD score, and long-term mechanical ventilation are significant risk factors for mortality in liver transplant patients with postoperative pulmonary complications. |
|
dc.source |
TRANSPLANTATION PROCEEDINGS |
|
dc.title |
Postoperative Pulmonary Complications After Liver Transplantation: |
|
dc.title |
Assessment of Risk Factors for Mortality |
|