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The in vitro toxicity analysis of titanium dioxide (TiO2) nanoparticles

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dc.contributor.author Ozgur, ME
dc.contributor.author Balcioglu, S
dc.contributor.author Ulu, A
dc.contributor.author Ozcan, I
dc.contributor.author Okumus, F
dc.contributor.author Koytepe, S
dc.contributor.author Ates, B
dc.date.accessioned 2022-08-09T08:28:39Z
dc.date.available 2022-08-09T08:28:39Z
dc.date.issued 2018
dc.identifier.uri http://hdl.handle.net/11616/60252
dc.description.abstract In recent years, titanium dioxide (TiO2) nanoparticles (NPs) as metal oxide nanoparticles are widely used in industry, agriculture, personal care products, cosmetics, sun protection and toothpaste, electronics, foodstuffs and food packaging. This use of nano-TiO2 has been associated with environmental toxicity concerns. Therefore, the aim of this study was to evaluate the in vitro effect of different doses of TiO2 NPs (similar to 30-40 nm) (0.01, 0.1, 0.5, 1, 10 and 50 mg/L) at 4oC for 3 h on the sperm cell kinematics as velocities of Rainbow trout (Oncorhynchus mykiss, Walbaum, 1792) sperm cells. Furthermore, oxidative stress markers (total glutathione (TGSH) and superoxide dismutase (SOD) were assessed in sperm cells after exposure to TiO2 NPs. According to the obtained results, there were statistically significant (P < 0.05) decreasing in the velocities of sperm cells after 10 mg/L TiO2 NPs and an increase the activity of SOD (P < 0.05) and TGSH levels were determined.
dc.description.abstract C1 [Ozgur, Mustafa Erkan] Inonu Univ, Fishery Fac, Dept Aquaculture, TR-44280 Malatya, Turkey.
dc.description.abstract [Balcioglu, Sevgi; Ulu, Ahmet; Ozcan, Imren; Koytepe, Suleyman; Ates, Burhan] Inonu Univ, Fac Sci, Dept Chem, TR-44280 Malatya, Turkey.
dc.description.abstract [Okumus, Fatih] Inonu Univ, Dogansehir Vahap Kucuk Vocat High Sch, Dept Comp Technol, TR-44280 Malatya, Turkey.
dc.source ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
dc.title The in vitro toxicity analysis of titanium dioxide (TiO2) nanoparticles
dc.title on kinematics and biochemical quality of rainbow trout sperm cells


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