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Analysis of urine biomarkers for early determination of acute kidney

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dc.contributor.author Elmas, AT
dc.contributor.author Karadag, A
dc.contributor.author Tabel, Y
dc.contributor.author Ozdemir, R
dc.contributor.author Otlu, G
dc.date.accessioned 2022-08-09T12:54:49Z
dc.date.available 2022-08-09T12:54:49Z
dc.date.issued 2017
dc.identifier.uri http://hdl.handle.net/11616/60316
dc.description.abstract Objective: We designed the present study to test the hypothesis that urinary biomarkers might predict acute kidney injury (AKI) development in non-septic and non-asphyxiated critically ill preterm infants. We evaluated urine (u) sistatin-C (uCys-C), kidney injury molecule-1 (uKIM-1) and neutrophil gelatinase associate lipocaline (uNGAL) as markers of AKI.
dc.description.abstract Methods: Sixty-four preterm infants with gestational age between 28 and 32 weeks were included in this study. Biomarkers were measured on day of life (DOL) 1, 3, and 7.
dc.description.abstract Results: uNGAL levels in the AKI group were significantly higher than in no-AKI group on DOL 1, 3 and 7 (p = 0.016, p = 0.007 and p = 0.0014, respectively).
dc.description.abstract Conclusions: uNGAL is sensitive, early, and noninvasive AKI biomarkers, increasing significantly in non-septic and non-asphyxiated critically ill preterm neonates.
dc.description.abstract C1 [Elmas, A. T.; Tabel, Y.] Inonu Univ, Fac Med, Dept Pediat Nephrol, Malatya, Turkey.
dc.description.abstract [Karadag, A.; Ozdemir, R.] Inonu Univ, Fac Med, Dept Neonatol, Malatya, Turkey.
dc.description.abstract [Otlu, G.] Inonu Univ, Fac Med, Dept Biochem, Malatya, Turkey.
dc.source JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
dc.title Analysis of urine biomarkers for early determination of acute kidney
dc.title injury in non-septic and non-asphyxiated critically ill preterm neonates


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