Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. Materials and Methods: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers. Demographic characteristics, clinical symptoms, signs at the admission, radiological findings, etiologic factors, acute and maintenance treatment, and outcome results were reported. The number of involved sinuses or veins, localizations of thrombus, and lesions on CT and MRI scans were recorded. Results: CH was detected in the brain imaging of 241 (21.1%) patients, as hemorrhagic infarction in 198 patients and intracerebral hemorrhage in 43 patients. Gynecologic causes comprised the largest percentage (41.7%) of etiology and risk factors in the CVST group. In the CH group, headache associated with other neurological symptoms was more frequent. These neurological symptoms were epileptic seizures (46.9%), nausea and/or vomiting (36.5%), altered consciousness (36.5%), and focal neurological deficits (33.6%). mRS was >= 3 in 23.1% of the patients in the CH group. Discussion and Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome.
C1 [Duman, Taskin; Colakog, Senalu] Mustafa Kemal Univ, Dept Neurol, Antakya, Turkey.
[Yayla, Vildan; Cabalar, Murat; Erdogan, Haci Ali] Univ Hlth Sci Bakirkoy Dr Sadi Konuk Res & Traini, Clin Neurol, Istanbul, Turkey.
[Uluduz, Derya; Goksan, Baki; Ince, Birsen] Istanbul Cerrahpasa Univ, Dept Neurol, Istanbul, Turkey.
[Goksu, Eylem Ozaydin; Tokuc, Firdevs Ezgi] Antalya Res & Training Hosp, Clin Neurol, Antalya, Turkey.
[Yurekli, Vedat Ali; Demirci, Seden] Suleyman Demirel Univ, Dept Neurol, Isparta, Turkey.
[Genc, Hamit; Yilmaz, Arda] Mersin Univ, Dept Neurol, Mersin, Turkey.
[Utku, Uygar; Gokce, Mustafa] Kahramanmaras Sutcu Imam Univ, Dept Neurol, Kahramanmaras, Turkey.
[Cinar, Nilgun; Sahin, Sevki; Tascilar, Nida] Maltepe Univ, Dept Neurol, Istanbul, Turkey.
[Tekeli, Hakan; Senol, Mehmet Guney; Ozdag, Fatih] Sultan Abdulhamid Han Res & Training Hosp, Clin Neurol, Istanbul, Turkey.
[Sungur, Mehmet Ali] Duzce Univ, Dept Biostat, Duzce, Turkey.
[Uzuner, Nevzat; Uzuner, Gulnur Tekgol] Osmangazi Univ, Dept Neurol, Eskisehir, Turkey.
[Kusbeci, Ozge Yilmaz] Bozyaka Educ Res & Training Hosp, Clin Neurol, Izmir, Turkey.
[Caglayan, Hale Zeynep Batur; Nazliel, Bijrn] Gazi Univ, Dept Neurol, Ankara, Turkey.
[Acikgoz, Mustafa] Bulent Ecevit Univ, Dept Neurol, Zonguldak, Turkey.
[Baybas, Sevim; Kucukoglu, Hayriye] Bakirkoy Res & Training Hosp Neurol & Psychiat Di, Clin Neurol, Istanbul, Turkey.
[Ekmekci, Hakan; Ozturk, Serefnur] Selcuk Univ, Dept Neurol, Konya, Turkey.
[Yaman, Mehmet; Oruc, Serdar] Afyon Kocatepe Univ, Dept Neurol, Afyon, Turkey.
[Bektas, Hesna] Ataturk Training & Res Hosp, Clin Neurol, Ankara, Turkey.
[Kaplan, Yuksel] Inonu Univ, Dept Neurol, Malatya, Turkey.
[Goksel, Basak Karakurum] Baskent Univ, Dept Neurol, Adana, Turkey.
[Milanlioglu, Aysel] Yuzuncu Yil Univ, Dept Neurol, Van, Turkey.
[Orken, Dilek Necioglu] Istanbul Bilim Univ, Dept Neurol, Istanbul, Turkey.
[Aluclu, Mehmet Ufuk] Dicle Univ, Dept Neurol, Diyarbakir, Turkey.
[Tufekci, Ahmet] Recep Tayyip Erdogan Univ, Dept Neurol, Rize, Turkey.
[Bakar, Mustafa] Uludag Univ, Dept Neurol, Bursa, Turkey.
[Kozak, Hasan Huseyin] Necmettin Erbakan Univ, Dept Neurol, Konya, Turkey.
[Misirli, Handan] Hlth Sci Univ, Haydarpasa Training & Res Hosp, Clin Neurol, Istanbul, Turkey.
[Midi, Ipek] Marmara Univ, Dept Neurol, Istanbul, Turkey.
[Mengulluoglu, Necdet] Eskisehir Govt Hosp, Clin Neurol, Eskisehir, Turkey.
[Aytac, Emrah] Ankara Res & Training Hosp, Clin Neurol, Ankara, Turkey.
[Yesilot, Nilufer] Istanbul Univ, Istanbul Fac Med, Dept Neurol, Istanbul, Turkey.
[Yalin, Osman Ozgur] Hlth Sci Univ, Istanbul Training & Res Hosp, Clin Neurol, Istanbul, Turkey.
[Gunes, Taskin] Maltepe Govt Hosp, Clin Neurol, Istanbul, Turkey.
[Domac, Fusun Mayda] Erenkoy Res & Training Hosp Neurol & Psychiat Dis, Istanbul, Turkey.
[Karahan, Ali] Usak Univ, Dept Phys Med & Rehabil, Usak, Turkey.
[Afsar, Nazire] Acibadem Univ, Dept Neurol, Istanbul, Turkey.