Helicobacter pylori Increases Gastric Compliance on Resected Stomach

Abstract

Background The relationship between high body mass index (BMI) and Helicobacter pylori (HP) was reported previously. But the mechanism is not clear. We aimed to evaluate the effect of HP on gastric compliance and volumes in obese patients. Materials and Methods One hundred fifty-nine patients who underwent sleeve gastrectomy due to morbid obesity were enrolled in the study and were divided into two groups as HP+ (n = 86) and HP- (n = 73) according to the HP status in resection materials. Demographics, pathological data, specimen sizes, volume, and compliance were retrospectively analyzed. Results The median age of the study group was 34 years (17-64 years) while the median BMI was 43 kg/m(2) (35-64, 3 kg/m(2)). Most of the patients (n = 134, 84.3%) were female. The median diameter of the widest point of the specimen was 22.5 cm (14-32 cm), and the median volume of the specimen was 790 cc (330-1920 cc). Both the diameter of the widest point and the volume of the specimens were significantly increased in the HP+ group compared to the HP- group (p < 0.001 and p = 0.017, respectively). In addition, the median compliance was 52.6 cc/mmHg, and the compliance was significantly higher (p < 0.001) in the HP+ group. There were no significant differences in specimen sizes between the two groups. Conclusion This is the first study showing that HP increases gastric compliance in obese patients who underwent LSG. The etiology and the effects of this increase in compliance have not been fully clarified yet. Further studies are needed to shed light on these effects.

C1 [Kaplan, Kuntay; Turgut, Emre; Okut, Gokalp] Inonu Univ, Dept Gastrointestinal Surg, Malatya, Turkey.

[Turgut, Emre] Inonu Univ, Dept Gastrointestinal Surg, Malatya, Turkey.

[Bag, Yusuf Murat] Hlth Sci Univ, Van Training & Res Hosp, Dept Gastrointestinal Surg, Van, Turkey.

[Sumer, Fatih] Irmet Hosp Int, Dept Gastrointestinal Surg, Cerkezkoy, Turkey.

[Kayaalp, Cuneyt] Yeditepe Univ, Dept Gastrointestinal Surg, Istanbul, Turkey.