Hearing status in vitamin B12-deficient children

Abstract

Aim The aim of this study is to investigate the effects of vitamin B12 deficiency on hearing in school-aged children by pure-tone audiometry.

Methods Forty-three vitamin B12-deficient children and 37 age-matched control subjects were enrolled in the study. Tympanometric evaluations and pure-tone audiometry including high frequencies were performed on the subjects. The results were compared between the two groups.

Results Both right and left ear pure-tone hearing thresholds (PTHTs) at 0.25-4 kHz, and four-frequency pure-tone average values were significantly better in the control group compared with the patient group (P < 0.05). However, PTHTs at 8-16 kHz were not different between the two groups (P > 0.05). Vitamin B12 level also did not show any significant correlation with the PTHTs at 0.25-16 kHz (P > 0.05).

Conclusion This study indicates that vitamin B12 deficiency may contribute to hearing impairment at low frequencies as a possible aetiological factor in children.

C1 [Akyay, Arzu] Inonu Univ, Dept Pediat Hematol & Oncol, Fac Med, Malatya, Turkey.

[Soylu, Erkan] Medipol Univ, Dept Otorhinolaryngol, Fac Med, Istanbul, Turkey.

[Unsal, Selim] Istinye Univ, Dept Language & Speech Therapy, Fac Hlth Sci, Istanbul, Turkey.

[Demirol, Hatice] Firat Univ, Dept Pediat Gastroenterol & Hepatol, Fac Med, Elazig, Turkey.

[Bahceci, Semiha] Cigli Training & Res Hosp, Dept Pediat Allergy & Immunologyy, Izmir, Turkey.