Middle-term outcomes in renal transplant recipients with COVID-19: a

Abstract

Background In this study, we evaluated 3-month clinical outcomes of kidney transplant recipients (KTR) recovering from COVID-19 and compared them with a control group. Method The primary endpoint was death in the third month. Secondary endpoints were ongoing respiratory symptoms, need for home oxygen therapy, rehospitalization for any reason, lower respiratory tract infection, urinary tract infection, biopsy-proven acute rejection, venous/arterial thromboembolic event, cytomegalovirus (CMV) infection/disease and BK viruria/viremia at 3 months. Results A total of 944 KTR from 29 different centers were included in this study (523 patients in the COVID-19 group; 421 patients in the control group). The mean age was 46 +/- 12 years (interquartile range 37-55) and 532 (56.4%) of them were male. Total number of deaths was 8 [7 (1.3%) in COVID-19 group, 1 (0.2%) in control group; P = 0.082]. The proportion of patients with ongoing respiratory symptoms [43 (8.2%) versus 4 (1.0%); P Conclusion The prevalence of ongoing respiratory symptoms increased in the first 3 months post-COVID in KTRs who have recovered from COVID-19, but mortality was not significantly different.

C1 [Oto, Ozgur Akin; Ozturk, Savas; Guller, Nurana; Yildiz, Alaattin] Istanbul Univ, Dept Internal Med, Div Nephrol, Istanbul Fac Med, Istanbul, Turkey.

[Arici, Mustafa; Koc, Neriman Sila] Hacettepe Univ, Dept Nephrol, Fac Med, Ankara, Turkey.

[Velioglu, Arzu; Kaya, Burcu] Marmara Univ, Sch Med, Dept Internal Med, Div Nephrol, Istanbul, Turkey.

[Dursun, Belda] Pamukkale Univ, Fac Med, Dept Internal Med, Div Nephrol, Denizli, Turkey.

[Sahin, Idris] Inonu Univ, Fac Med, Dept Internal Med, Nephrol Div, Malatya, Turkey.

[Eser, Zeynep Ebru] Mersin Univ, Mersin Fac Med, Dept Internal Med, Div Nephrol, Mersin, Turkey.

[Paydas, Saime] Cukurova Univ, Dept Internal Med, Div Nephrol, Fac Med, Adana, Turkey.

[Trabulus, Sinan; Seyahi, Nurhan] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Div Nephrol, Dept Internal Med, Istanbul, Turkey.

[Koyuncu, Sumeyra] Erciyes Univ, Erciyes Fac Med, Dept Internal Med, Div Nephrol, Kayseri, Turkey.

[Uyar, Murathan] Yeni Yuzyil Univ, Gaziosmanpasa Hosp, Div Nephrol, Dept Internal Med, Istanbul, Turkey.

[Ural, Zeynep] Gazi Univ, Fac Med, Dept Internal Med, Div Nephrol, Ankara, Turkey.

[Sadioglu, Rezzan Eren; Ates, Kenan] Ankara Univ, Dept Nephrol, Sch Med, Ankara, Turkey.

[Dheir, Hamad] Sakarya Univ Training & Res Hosp, Div Nephrol, Dept Internal Med, Sakarya, Turkey.

[Ozer, Hakan] Konya Necmettin Erbakan Univ, Meram Fac Med, Div Nephrol, Konya, Turkey.

[Durak, Beyza Algul] Ankara Bilkent City Hosp, Dept Nephrol, Ankara, Turkey.

[Gul, Cuma Bulent] Univ Hlth Sci, Bursa Yuksek Ihtisas Training & Res Hosp, Dept Nephrol, Istanbul, Turkey.

[Kasapoglu, Umut] Univ Hlth Sci, Bakirkoy Dr Sadi Konuk Training & Res Hosp, Dept Nephrol, Istanbul, Turkey.

[Oguz, Ebru Gok] Univ Hlth Sci, Diskapi Yildirim Beyazit Educ & Res Hosp, Dept Nephrol, Ankara, Turkey.

[Tanrisev, Mehmet] Univ Hlth Sci, Tepecik Training & Res Hosp, Izmir Fac Med, Dept Nephrol, Izmir, Turkey.

[Kuzgun, Gulsah Sasak] Gortepe Prof Dr Suleyman Yalcin City Hosp, Dept Nephrol, Istanbul, Turkey.

[Mirioglu, Safak] Bezmialem Vakif Univ, Dept Internal Med, Div Nephrol, Sch Med, Istanbul, Turkey.

[Dervisoglu, Erkan] Kocaeli Univ, Fac Med, Dept Internal Med, Div Nephrol, Kocaeli, Turkey.

[Erken, Ertugrul; Gungor, Ozkan] Kahramanmaras Sutcu Imam Univ, Dept Nephrol, Kahramanmaras, Turkey.

[Gorgulu, Numan] Univ Hlth Sci, Bagcilar Training & Res Hosp, Dept Nephrol, Istanbul, Turkey.

[Ozkurt, Sultan] Eskisehir Osmangazi Univ, Fac Med, Dept Internal Med, Div Nephrol, Eskisehir, Turkey.

[Aydin, Zeki] Univ Hlth Sci, Darica Farabi Training & Res Hosp, Dept Nephrol, Darica, Turkey.

[Kurultak, ilhan] Trakya Univ, Fac Med, Dept Internal Med, Div Nephrol, Edirne, Turkey.

[Ogutmen, Melike Betul] Univ Hlth Sci, Haydarpasa Numune Training & Res Hosp, Dept Nephrol, Istanbul, Turkey.

[Bakirdogen, Serkan] Canakkale Onsekiz Mart Univ, Sch Med, Dept Internal Med, Div Nephrol, Canakkale, Turkey.

[Karadag, Serhat] Univ Hlth Sci, Haseki Training & Res Hosp, Dept Nephrol, Istanbul, Turkey.

[Ulu, Memnune Sena] Bahcesehir Univ, Fac Med, Dept Internal Med, Div Nephrol, Istanbul, Turkey.

[Bakir, Elif Ari] Univ Hlth Sci, Kartal Training Hosp, Dept Internal Med, Div Nephrol, Istanbul, Turkey.

[Odabas, Ali Riza] Univ Hlth Sci, Sultan 2 Abdulhamid Han Training & Res Hosp, Dept Nephrol, Istanbul, Turkey.