Purpose Hematuria is one of the most common laboratory findings in nephrology practice. To date, there is no enough data regarding the clinical and histopathologic characteristics of primary glomerular disease (PGD) patients with hematuria in our country. Methods Data were obtained from national multicenter (47 centers) data entered into the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) database between May 2009 and June 2019. The data of all PGD patients over the age of 16 years who were diagnosed with renal biopsy and had hematuria data were included in the study. Demographic characteristics, laboratory and biopsy findings were also recorded. Results Data of 3394 PGD patients were included in the study. While 1699 (50.1%) patients had hematuria, 1695 (49.9%) patients did not have hematuria. Patients with hematuria had statistically higher systolic blood pressure, serum blood urea nitrogen, creatinine, albumin, levels and urine pyuria. However, these patients had statistically lower age, body mass index, presence of hypertension and diabetes, eGFR, 24-h proteinuria, serum total, HDL and LDL cholesterol, and C3 levels when compared with patients without hematuria. Hematuria was present 609 of 1733 patients (35.8%) among the patients presenting with nephrotic syndrome, while it was presented in 1090 of 1661 (64.2%) patients in non-nephrotics (p < 0.001). Conclusion This is the first multicenter national report regarding the demographic and histopathologic data of PGD patients with or without hematuria. Hematuria, a feature of nephritic syndrome, was found at a higher than expected in the PGDs presenting with nephrotic syndrome in our national database.
C1 [Sumnu, Abdullah] Medipol Univ, Med Fac, Dept Nephrol, Medipol Mega Hastanesi, Goztepe Mahallesi Metin Sk 4, Istanbul, Turkey.
[Turkmen, Kultigin] Necmettin Erbakan Univ, Meram Med Fac, Nephrol, Konya, Turkey.
[Cebeci, Egemen; Uzun, Sami; Ozturk, Savas] Haseki Training & Res Hosp, Nephrol, Istanbul, Turkey.
[Turkmen, Aydin] Istanbul Univ, Istanbul Med Fac, Nephrol, Istanbul, Turkey.
[Eren, Necmi; Ergul, Metin] Kocaeli Univ, Nephrol Med Fac, Kocaeli, Turkey.
[Seyahi, Nurhan; Dincer, Mevlut Tamer] Istanbul Univ, Cerrahpasa Med Fac, Nephrol, Istanbul, Turkey.
[Oruc, Aysegul; Gullulu, Mustafa] Uludag Univ, Med Fac, Nephrol, Bursa, Turkey.
[Dede, Fatih; Piskinpasa, Serhan] Ankara Numune Training & Res Hosp, Nephrol, Ankara, Turkey.
[Derici, Ulver; Akcay, Omer Faruk] Gazi Univ, Med Fac, Nephrol, Ankara, Turkey.
[Basturk, Taner; Unsal, Abdulkadir] Hamidiye Sisli Etfal Training & Res Hosp, Nephrol, Istanbul, Turkey.
[Sahin, Garip] Eskisehir Osmangazi Univ, Med Fac, Nephrol, Eskisehir, Turkey.
[Sipahioglu, Murat; Koyuncu, Sumeyra] Erciyes Univ, Med Fac, Nephrol, Kayseri, Turkey.
[Sahin, Gulizar Manga; Gok, Mahmut] Sultan Abdulhamit Han Res & Training Hosp, Nephrol, Istanbul, Turkey.
[Tatar, Erhan] Bozyaka Training & Res Hosp, Nephrol, Izmir, Turkey.
[Dursun, Belda] Pamukkale Univ, Med Fac, Nephrol, Denizli, Turkey.
[Sipahi, Savas] Sakarya Univ, Med Fac, Nephrol, Sakarya, Turkey.
[Yilmaz, Murvet] Bakirkoy Sadi Konuk Training & Res Hosp, Nephrol, Istanbul, Turkey.
[Suleymanlar, Gultekin] Akdeniz Univ, Med Fac, Nephrol, Antalya, Turkey.
[Ulu, Sena] Afyon Kocatepe Univ, Med Fac, Nephrol, Afyon, Turkey.
[Gungor, Ozkan] Sutcu Imam Univ, Med Fac, Nephrol, Kahramanmaras, Turkey.
[Kutlay, Sim] Ankara Univ, Ibni Sina Hosp, Med Fac, Nephrol, Ankara, Turkey.
[Bahcebasi, Zerrin Bicik] Dr Lutfi Kirdar Kartal Training & Res Hosp, Nephrol, Istanbul, Turkey.
[Sahin, Idris] Inonu Univ, Med Fac, Nephrol, Malatya, Turkey.
[Kurultak, Ilhan] Trakya Univ, Med Fac, Nephrol, Edirne, Turkey.
[Sevinc, Can] Ataturk Univ, Med Fac, Nephrol, Erzurum, Turkey.
[Yilmaz, Zulfikar] Dicle Univ, Diyarbakir, Turkey.
[Kazancioglu, Rumeyza Turan] Bezmialem Vakif Univ, Med Fac, Nephrol, Istanbul, Turkey.
[Cavdar, Caner] Dokuz Eylul Univ, Med Fac, Nephrol, Izmir, Turkey.
[Candan, Ferhan] Cumhuriyet Univ, Med Fac, Nephrol, Sivas, Turkey.
[Aydin, Zeki] Darica Farabi Training & Res Hosp, Nephrol, Kocaeli, Turkey.
[Oygar, Deren] Burhan Nalbantoglu State Hosp, Nephrol, Nicosia, Cyprus.
[Gul, Bulent] Bursa Yuksek Ihtisas Training & Res Hosp, Nephrol, Bursa, Turkey.
[Altun, Bulent] Hacettepe Univ, Med Fac, Nephrol, Ankara, Turkey.
[Paydas, Saime] Cukurova Univ, Med Fac, Nephrol, Adana, Turkey.
[Istemihan, Zulal] Istanbul Univ, Istanbul Med Fac, Internal Med, Istanbul, Turkey.