dc.contributor.author |
Göğcegöz Gül, Işıl |
|
dc.contributor.author |
Karlıdağ, Rıfat |
|
dc.contributor.author |
Cumurcu, Hatice Birgül |
|
dc.contributor.author |
Türköz, Yusuf |
|
dc.contributor.author |
Özcan, Abdul Cemal |
|
dc.contributor.author |
Erdemli, Erman |
|
dc.date.accessioned |
2017-05-19T11:50:27Z |
|
dc.date.available |
2017-05-19T11:50:27Z |
|
dc.date.issued |
2013 |
|
dc.identifier.citation |
Göğcegöz Gül, I. Karlıdağ, R. Cumurcu, H. B. Türköz, Y. Özcan, A. C. Erdemli, E. (2013). The effect of agoraphobia on oxidative stress in panic disorder. Psychiatry Investigation 10(4), 317–325. |
tr_TR |
dc.identifier.issn |
1738-3684 |
|
dc.identifier.uri |
http://synapse.koreamed.org/DOIx.php?id=10.4306/pi.2013.10.4.317 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/6907 |
|
dc.description.abstract |
We aimed to investigate whether agoraphobia (A) in panic disorder (PD) has any effects on oxidative and anti-oxidative parameters. We
measured total antioxidant capacity (TAC), paraoxonase (PON), arylesterase (ARE) antioxidant and malondialdehyde (MDA) oxidant
levels using blood samples from a total of 31 PD patients with A, 22 PD patients without A and 53 control group subjects. There was a
significant difference between the TAC, PON, ARE and MDA levels of the three groups consisting of PD with A, PD without A and the
control group. The two-way comparison to clarify the group creating the difference showed that the TAC, PON, and ARE antioxidants
were significantly lower in the PD with A group compared to the control group while the MDA oxidant was significantly higher. There
was no significant difference between the PD without A and control groups for TAC, PON, ARE and MDA levels. We clearly demonstrated
that the oxidative stress and damage to the anti-oxidative mechanism are significantly higher in the PD group with A. These findings
suggest that oxidative/anti-oxidative mechanisms may play a more important role on the pathogenesis of PB with A. |
tr_TR |
dc.language.iso |
eng |
tr_TR |
dc.publisher |
Psychiatry Investigation |
tr_TR |
dc.relation.isversionof |
10.4306/pi.2013.10.4.317 |
tr_TR |
dc.rights |
info:eu-repo/semantics/openAccess |
tr_TR |
dc.subject |
Agoraphobia |
tr_TR |
dc.subject |
Free radical |
tr_TR |
dc.subject |
Panic disorder |
tr_TR |
dc.subject |
Oxidative stress |
tr_TR |
dc.subject |
Total antioxidant capacity |
tr_TR |
dc.title |
The effect of agoraphobia on oxidative stress in panic disorder |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.journal |
Psychiatry Investigation |
tr_TR |
dc.contributor.department |
İnönü Üniversitesi |
tr_TR |
dc.identifier.volume |
10 |
tr_TR |
dc.identifier.issue |
4 |
tr_TR |
dc.identifier.startpage |
317 |
tr_TR |
dc.identifier.endpage |
325 |
tr_TR |