Amaç: Kekemelik seslerin, hecelerin ve kelimelerin istemsiz
tekran ve uzatilmasi ile konuima akiciliginin bozuldugu,
nedeni tarn olarak bilinmeyen bir konu^ma bozuklugudur.
Konuimanin akiciligjn saglanmasinda psikolojrk sosyal,
ögrenme ¡le ilt^kilí unsurlar ve sensorimotor degijkenler
önemli rol oynar. Beynin gelen uyanlari islemlemesinde ve
uygun bir davranissal yanit olujturulmasinda duyusal kapilama
gerekli bir ijlemdir. Duyusal kapilama, sinirli bi!gi ijleme
kapasitesine sahip olan beyni, siirekii ve yogun bilgi
akiii sirasmda gereginden fazia veya ili}kisiz olan uyaranlarin
filtrelenmesini saglayarak ajiri yüklenmeden korur. l^itsel
uyaranlann kapilanamamasi, i^itsel sinyallerin ijlenmesi
ve i^itsel geribildirim mekanizmasini da bozarak konujma
akiciliginm bozulmasina yol açabilir. Çalifmamizda kekemelikte
duyusal kapilamanin bozulmuj olabilecegi hipotezjni
test etmek i(;ir) gelijimsel kekemeligi olan çocuk ve ergenlerde
duyusal kapilamanin durumunu P50 supresyonu
ile degerlendirmeyi amaçladik.
Yöntem; Calijmaya gelisimsel kekemeligi oian 7-18 yaj
araliginda 20 çocuk ve etgen ile, konujma problemi olmayan
yaj ve cinsiyet açismdan birebir eíleítirilmi} 20 saglikli
kontrol alindi. Tüm olgulara bir çocuk psikiyatristi tarafindan
psikiyatrik degerlendirme yapildi. Psikiyatrik, nörolojik
ve kronik hastaligi olan, santral sinir sistemini etkileyen ilaç
kullanim öyküsü ve ailesinde sizofreni öykusü olan olgular
çalijma diji birakiidi. Tüm bu degerlendirmeierin ardindan
P 50 supresyon degerlendirmesi elektroensefologram
(EEG) ile kaydedildi. Cali^manin istatistiksel analizi SPSS paket
programi kullanilarak yapildi. Her iki grubun P50 degerlerini
kafiilajtifmak için Mann-Whitney U testi kuNanildi ve
tüm anaiizlerde p<0.05 anlamlilik derececesi olarak kabul
edildi.
Bulgular: Çalijmada yer alan çocuk ve ergenlerin yaj ortalamasi
11,8 ±2,7, kekemelik bajlama ya^i 4,6±1,1 idi. Çalijmaya
kalilanlann her iki grupta da 16'si |%80) erkek 4'ü (%
20) kizdi. Her iki grubun P50 amplitüt, latans, P50 supresyon
oranlari arasinda istatistiksel olarak anlamli fark saptanmadi.
Sonuç: Bu cali^manin sonuçlari çocuk ve ergenlerde P50 ile
kekemelik arasmda bir ili^ki olmadigmi ortaya koymaktadir.
Ancak kekeme çocuk ve ergenlerde duyusal kapilamayí degerlendiren
bu ilk çali^ma. duyusal kapilamayí degerlendirmede
kullanilan diger bir test oian prepulse inhibisyonla
da, farklt yaj gruplannda ve daha genij örneklem üzerinde
tekrarlanmalidir.
Objective: Stuttering is a speech disorder, where speech
fluency is disturbed by the involuntary repetition and
prolongation of words and syllables. Its cause is not fully
known. Sensory gating is an essential part of information
processing and developing an appropriate behavioral
response in the brain. Psychological, social, and learningrelated
factors together with sensorymotor variables play
an important role in ensuring fluent speech. Sensory
gating protects the brain from overload by filtering the
redundant or potentially irrelevant information from the
continuous and intensive stream of information. A lack of
sensory gating for auditory stimuli may lead to disturbed
auditory signal processing and auditory feedback and
result in loss of speech fluency. Our aim in this study was to
evaluate the state of sensory gating in children and
adolescents with developmental stuttering using P50
suppression to test our hypothesis that sensory gating may
be disturbed in stuttering.
Method: A total of 20 stuttering children and adolescents
in 7-18 age group and 20 age-and sex-matched healthy
controis with no speech problems were included in the
study. All children underwent psychiatric evaluation by a
pédiatrie psychiatrist. Patients with psychiatric,
neurological or chronic disease, those who had a history of
using medication that could affect the central nervous
system and children with a family history of schizophrenia
were excluded from the study. P50 suppression was then
recorded with an elearoencephalogram (EEG). Statistical
analysis was performed using the SPSS package software
program. The Mann-Whitney U test was used to compare
the P50 values of the two groups and p value <0.05 was
considered significant for all analyses.
Results: The mean age for the children and adolescents
included in the study was 11.8±2.7 years and the age
stuttering started was 4.6±1.1 years. There were 16 males
(80%) and 4 females (20%) in both groups. There was no
statistically significant difference between the P50 amplitude,
latency and P50 suppression ratios of the two groups.
Conclusion: The results of this study have shown no
association between P50 and stuttering in children and
adolescents. However, this first study evaluating sensory
gating in children and adolescents should be repeated
with prepuise inhibition, another test used to evaluate
sensory gating, on larger samples and in different age
groups.
