dc.contributor.author |
Alkan, Alpay |
|
dc.contributor.author |
Kutlu, Ramazan |
|
dc.contributor.author |
Tarık, Hallaç |
|
dc.contributor.author |
Sığırcı, Ahmet |
|
dc.contributor.author |
Emul, Murat |
|
dc.contributor.author |
Pala, Nilgün |
|
dc.contributor.author |
Altınok, Tayfun |
|
dc.contributor.author |
Aslan, Mehmet |
|
dc.contributor.author |
Saraç, Kaya |
|
dc.contributor.author |
Özcan, Abdulcemal |
|
dc.date.accessioned |
2017-05-22T11:06:07Z |
|
dc.date.available |
2017-05-22T11:06:07Z |
|
dc.date.issued |
2004 |
|
dc.identifier.citation |
Alkan, A. Kutlu, R. Tarık, H. Sığırcı, A. Emul, M. Pala, N. Altınok, T. Aslan, M. Saraç, K. Özcan, A. (2004). Occupational prolonged organic solvent exposure in shoemakers brain MR spectroscopy findings. Magnetic Resonance Imaging, 22(5), 707–713. |
tr_TR |
dc.identifier.issn |
0730725X |
|
dc.identifier.uri |
http://linkinghub.elsevier.com/retrieve/pii/S0730725X04001092 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/6928 |
|
dc.description.abstract |
Our purpose was to investigate, by magnetic resonance (MR) spectroscopy, the metabolite changes in the brains of subjects in the
shoemaking industry who had been chronically exposed to organic solvents. A total of 49 male subjects and 30 age-matched healthy
volunteers underwent detailed neurological and psychiatric examinations. All subjects had long-echo [repetition time (TR) 2000 ms, echo
time (TE) 136 ms] single-voxel MR spectroscopy. Voxels (15 15 15 mm3
) were placed in the parietal white matter, thalamus, and basal
ganglia. N-acetylaspartate (NAA)/creatine (Cr) and choline (Cho)/Cr ratios were calculated. There was no significant difference between
the study subjects and the control group in NAA/Cr ratios obtained from thalamus, basal ganglia, and parietal white matter. Cho/Cr ratios
in thalamus, basal ganglia, and parietal white matter were found to be significantly increased compared to controls. There was a positive correlation
between basal ganglia Cho/Cr ratio and duration of exposure (r 0.63). MR spectroscopy should be performed to reveal metabolite changes
and determine the degree of brain involvement in solvent-related industry workers. |
tr_TR |
dc.language.iso |
eng |
tr_TR |
dc.publisher |
Magnetic Resonance Imaging |
tr_TR |
dc.relation.isversionof |
10.1016/j.mri.2004.01.070 |
tr_TR |
dc.rights |
info:eu-repo/semantics/openAccess |
tr_TR |
dc.subject |
Occupational exposure |
tr_TR |
dc.subject |
Solvents |
tr_TR |
dc.subject |
Magnetic resonance spectroscopy |
tr_TR |
dc.title |
Occupational prolonged organic solvent exposure in shoemakers brain MR spectroscopy findings |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.journal |
Magnetic Resonance Imaging |
tr_TR |
dc.contributor.department |
İnönü Üniversitesi |
tr_TR |
dc.identifier.volume |
22 |
tr_TR |
dc.identifier.issue |
5 |
tr_TR |
dc.identifier.startpage |
707 |
tr_TR |
dc.identifier.endpage |
713 |
tr_TR |