Özet:
Boron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies
identified only few genes related to boron metabolism thus far and details of how boron is imported into cells
and used in cell metabolism are largely unknown. In order to identify genes that play roles in boron
metabolism, we screened the entire set of yeast haploid deletion mutants and identified 6 mutants that were
resistant to toxic levels of boron, and 21 mutants that were highly sensitive to boron treatment. Furthermore,
we performed a proteomic approach to identify additional proteins that are significantly up-regulated by
boron treatment. Our results revealed many genes and pathways related to boron stress response and suggest
a possible link between boron toxicity and translational control.
