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Subacute sclerosing panencephalitis relationship between clinical stage and diffusion weighted imaging findings

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dc.contributor.author Alkan, Alpay
dc.contributor.author Korkmaz, Levent
dc.contributor.author Sığırcı, Ahmet
dc.contributor.author Kutlu, Ramazan
dc.contributor.author Yakıncı, Mehmet Cengiz
dc.contributor.author Erdem, Gülnur
dc.contributor.author Yoloğlu, Saim
dc.date.accessioned 2017-06-23T06:55:04Z
dc.date.available 2017-06-23T06:55:04Z
dc.date.issued 2006
dc.identifier.citation Alkan, A. Korkmaz, L. Sığırcı, A. Kutlu, R. Yakıncı, M. C. Erdem, G. Yoloğlu, S. (2006). Subacute sclerosing panencephalitis relationship between clinical stage and diffusion weighted imaging findings. J Magn Reson Imaging, (23), 267–272. tr_TR
dc.identifier.uri http://onlinelibrary.wiley.com/doi/10.1002/jmri.20518/abstract
dc.identifier.uri http://hdl.handle.net/11616/7146
dc.description.abstract To investigate the relationship between clinical stages and apparent diffusion coefficient (ADC) changes in the brain of patients with subacute sclerosing panencephalitis (SSPE). Materials and Methods: A total of 18 patients with stage II (N 11) and III (N 7) SSPE and 11 age-matched controls underwent routine MRI and diffusion-weighted imaging (DWI). The ADC values were automatically calculated. Seven distinct neuroanatomic structures (frontal, parieto-occipital, and cerebellar white matter; deep white matter; thalamus; basal ganglia; and brainstem) were selected for analysis in the patient and control groups. Results: Hyperintensities in the periventricular and subcortical white matters on T2-weighted images and ADC maps were detected in 63.6% of patients with stage II and in all patients with stage III. There were significant differences between stage II and III patients and also between patients and control group in ADC values that obtained from all locations. The highest mean ADC values were calculated in stage III patients. Although MRI and DWI findings were normal in four patients with stage II disease, ADC values were significantly increased when compared with controls. Conclusion: The stage of disorder may be independent of DWI appearance during the early stage (stages I and II), even though the brain is affected. Therefore, DWI and ADC values supplemental to routine MRI should also be utilized for lesion detection and definition to enhance diagnostic accuracy in patients with SSPE. tr_TR
dc.language.iso eng tr_TR
dc.publisher J Magn Reson Imaging tr_TR
dc.rights info:eu-repo/semantics/openAccess tr_TR
dc.subject Subacute sclerosing panencephalitis tr_TR
dc.subject MRI tr_TR
dc.subject Diffusion-weighted imaging tr_TR
dc.subject Apparent diffusion coefficient tr_TR
dc.subject Stage tr_TR
dc.title Subacute sclerosing panencephalitis relationship between clinical stage and diffusion weighted imaging findings tr_TR
dc.type article tr_TR
dc.relation.journal J Magn Reson Imaging tr_TR
dc.contributor.department İnönü Üniversitesi tr_TR
dc.contributor.authorID 7768 tr_TR
dc.identifier.volume 23 tr_TR
dc.identifier.startpage 267 tr_TR
dc.identifier.endpage 272 tr_TR


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