dc.contributor.author |
Kayhan, Başak |
|
dc.contributor.author |
Araslı, Mehmet |
|
dc.contributor.author |
Eren, Hacı |
|
dc.contributor.author |
Aydemir, Selim |
|
dc.contributor.author |
Aktaş, Elif |
|
dc.date.accessioned |
2017-08-03T11:11:57Z |
|
dc.date.available |
2017-08-03T11:11:57Z |
|
dc.date.issued |
2008 |
|
dc.identifier.citation |
Kayhan, B. Araslı, M. Eren, H. Aydemir, S. Aktaş, E. (2008). Analysis of peripheral blood lymphocyte phenotypes and Th1 Th2 cytokines profile in the systemic immune responses ofHelicobacter pylori infected individuals. Microbiology and Immunology . 52(11), 531–538. |
tr_TR |
dc.identifier.issn |
03855600 |
|
dc.identifier.uri |
http://doi.wiley.com/10.1111/j.1348-0421.2008.00066.x |
|
dc.identifier.uri |
http://hdl.handle.net/11616/7435 |
|
dc.description.abstract |
H. pylori elicits specific humoral and cellularimmune responsesin themucosalimmune system.However,
the type and extent of T lymphocyte response in the systemic immune system is not clear for H. pylori
positive patients. In this study, peripheral blood T lymphocyte phenotypes and serum Th1/Th2 based
cytokines of 32 H. pylori positive patients were analyzed and compared to those of healthy controls.
While αβ TCR+ lymphocytes and their phenotype analysis were not significantly different to those of
healthy controls, the percentage of pan γδ TCR+ lymphocytes was up to 2.4 times greater in the H. pylori
positive group then in healthy controls. Furthermore, significant increases in IL-10 concentrations in
serum samples of H. pylori patients indicated that their immune systems had switched toward a Th2
type immune response. The correlation between phenotype and type of T cell response in the peripheral
blood during H. pylori infection is discussed. |
tr_TR |
dc.language.iso |
eng |
tr_TR |
dc.publisher |
Microbiology and Immunology |
tr_TR |
dc.relation.isversionof |
10.1111/j.1348-0421.2008.00066.x |
tr_TR |
dc.rights |
info:eu-repo/semantics/openAccess |
tr_TR |
dc.subject |
Cytokines |
tr_TR |
dc.subject |
Gamma delta T cells |
tr_TR |
dc.subject |
Helicobacter pylori |
tr_TR |
dc.subject |
Immunophenotyping |
tr_TR |
dc.title |
Analysis of peripheral blood lymphocyte phenotypes and Th1 Th2 cytokines profile in the systemic immune responses ofHelicobacter pylori infected individuals |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.journal |
Microbiology and Immunology |
tr_TR |
dc.contributor.department |
İnönü Üniversitesi |
tr_TR |
dc.contributor.authorID |
41809 |
tr_TR |
dc.identifier.volume |
52 |
tr_TR |
dc.identifier.issue |
11 |
tr_TR |
dc.identifier.startpage |
531 |
tr_TR |
dc.identifier.endpage |
538 |
tr_TR |