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ABO incompatible liver transplantation in acute and acute on chronic liver failure

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dc.contributor.author Yılmaz, Sezai
dc.contributor.author Aydın, Cemalettin
dc.contributor.author Işık, Burak
dc.contributor.author Kayaalp, Cüneyt
dc.contributor.author Yılmaz, Mehmet
dc.contributor.author Ara, Cengiz
dc.contributor.author Kutlu, Ramazan
dc.contributor.author Bayındır, Yaşar
dc.contributor.author Ersan, Veysel
dc.date.accessioned 2017-11-09T06:11:55Z
dc.date.available 2017-11-09T06:11:55Z
dc.date.issued 2013
dc.identifier.citation Yılmaz, S., Aydın, C., Işık, B., Kayaalp, C., Yılmaz, M., Ara, C., … Ersan, V. (2013). Abo İncompatible Liver Transplantation İn Acute And Acute On Chronic Liver Failure . Hepato-Gastroenterology, 60(125), 1189–93. tr_TR
dc.identifier.uri https://www.ncbi.nlm.nih.gov/pubmed/23478144
dc.identifier.uri http://hdl.handle.net/11616/7840
dc.description Hepatogastroenterology. 2013 Jul-Aug;60(125):1189-93. tr_TR
dc.description.abstract BACKGROUND/AIMS: ABO-incompatible (ABO-I) liver transplantation (LTx) may be mandatory in urgent conditions such as acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) when deceased donor (DD) is unavailable or living donor (LD) selection is limited. This study specifically addresses the problem of urgent ABO-I LTx in critically ill adult patients having ALF or severely decompensated end-stage liver disease. METHODOLOGY: This series included 16 patients, 10 underwent ABO-I LD LTx and 6 underwent 7 ABO-I DD LTx. Multiple sessions of plasmapheresis reduced isoaglutinin titres to 1/16 or below, before and after LTx. RESULTS: Mean follow-up period was 10.37 months (1 to 38). Median for MELD scores was 22.5 (17 to 30). Median survival was 9 months and mean survival was 19.5 months. Hospital mortality was 3 (18.7%). Two patients died due to small for size graft syndrome and cerebrovascular bleeding respectively. Hepatic artery thrombosis developed in 3 patients. Two of them died at postoperative 4th and 9th months. Third patient is still alive with hepatic necrosis problem. CONCLUSIONS: ABO-I LTx remains an important and unavoidable therapeutic option in adult patients with ALF or ACLF and urgent need for an allograft without the possibility to allocate a blood group compatible liver graft. tr_TR
dc.language.iso eng tr_TR
dc.publisher Hepato-gastroenterology tr_TR
dc.relation.isversionof Hepato-gastroenterology tr_TR
dc.rights info:eu-repo/semantics/openAccess tr_TR
dc.title ABO incompatible liver transplantation in acute and acute on chronic liver failure tr_TR
dc.type article tr_TR
dc.relation.journal Hepato-gastroenterology tr_TR
dc.contributor.department İnönü Üniversitesi tr_TR
dc.contributor.authorID 112689 tr_TR
dc.contributor.authorID 131825 tr_TR
dc.contributor.authorID 109262 tr_TR
dc.contributor.authorID 109416 tr_TR
dc.contributor.authorID 130755 tr_TR
dc.contributor.authorID 123849 tr_TR
dc.contributor.authorID 110105 tr_TR
dc.identifier.volume 60 tr_TR
dc.identifier.issue 125 tr_TR
dc.identifier.startpage 1189 tr_TR
dc.identifier.endpage 1193 tr_TR

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