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Right lobe living donor liver transplantation in adult patients with acute liver failure

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dc.contributor.author Ateş, Mustafa
dc.contributor.author Hatipoğlu, Hamit Sinan
dc.contributor.author Dirican, Abuzer
dc.contributor.author Işık, Burak
dc.contributor.author İnce, Volkan
dc.contributor.author Yılmaz, Sezai
dc.contributor.author Aydın, Cemalettin
dc.contributor.author Ara, Cengiz
dc.contributor.author Kayaalp, Cüneyt
dc.contributor.author Yılmaz, Sezai
dc.date.accessioned 2017-11-28T11:14:53Z
dc.date.available 2017-11-28T11:14:53Z
dc.date.issued 2013
dc.identifier.citation Ateş, M., Hatipoğlu, H. S., Dirican, A., Işık, B., İnce, V., Yılmaz, M., … Yılmaz, S. (2013). Right Lobe Living Donor Liver Transplantation İn Adult Patients With Acute Liver Failure. Transplantation Proceedings, 45(5), 1948–1952. tr_TR
dc.identifier.uri http://akademik.yok.gov.tr/AkademikArama/view/viewAuthorArticle.jsp
dc.identifier.uri http://hdl.handle.net/11616/7843
dc.description.abstract Background. Right-lobe living-donor liver transplantation (RLDLT) is an excellent option to reduce donor shortages for adult patients with acute liver failure (ALF). The aim of this study was to evaluate the etiologies and outcomes of 30 consecutive adult patients who underwent emergency RLDLT for ALF. Methods. Between January 2007 and September 2011, we examined data from medical records of patients with ALF who underwent RLDLT. Results. Their mean age was 32.2 13.05 years. The etiologies of ALF were acute hepatitis B (n 11; 36.6%), hepatitis A (n 4; 13.3%), drug intoxication (n 4; 13.3%), pregnancy (n 2; 6.7%), hepatitis B with pregnancy (n 1; 3.3%), mushroom intoxication (n 1; 3.3%), and unknown (n 7; 23.3%). The mean hepatic coma grade (Model for End-Stage Liver Disease score) was 34.13 8.72. The 43 (48.7%) postoperative complications were minor (grades I–II) and 44 (51.3%) were major (grades III–V). Reoperation was required in 14 of 30 (47%) recipients (grades IIIb–IVa). Deaths occurred owing to pulmonary (n 2), cardiac (n 1), septic (n 2), or encephalopathic (n 4) complications. The mean durations of intensive care unit stay and postoperative hospitalization were 3.2 2.3 and 29.5 23 days, respectively. The survival rate was 70%. The mean follow-up duration was 305 days (range, 1–1582). Conclusion. Liver transplantation is potentially the only curative modality, markedly improving the prognosis of patients with ALF. The interval between ALF onset and death is short and crucial because of the rapid, progressive multiorgan failure. Thus, RLDLT should be considered to be a life-saving procedure for adult patients with ALF, requiring quicker access to a deceased-donor liver graft and a short ischemia time. tr_TR
dc.language.iso eng tr_TR
dc.publisher Transplantation Proceedings tr_TR
dc.relation.isversionof 10.1016/j.transproceed.2012.10.056 tr_TR
dc.rights info:eu-repo/semantics/openAccess tr_TR
dc.title Right lobe living donor liver transplantation in adult patients with acute liver failure tr_TR
dc.type article tr_TR
dc.relation.journal Transplantation Proceedings tr_TR
dc.contributor.department İnönü Üniversitesi tr_TR
dc.contributor.authorID 112689 tr_TR
dc.contributor.authorID 110105 tr_TR
dc.contributor.authorID 114041 tr_TR
dc.contributor.authorID 116248 tr_TR
dc.contributor.authorID 28465 tr_TR
dc.contributor.authorID 109416 tr_TR
dc.identifier.volume 45 tr_TR
dc.identifier.issue 5 tr_TR
dc.identifier.startpage 1948 tr_TR
dc.identifier.endpage 1952 tr_TR

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