Objective. To develop and assess the validity and reliability of an adherence scale concerning medical treatment in paediatric FMF patients.
Methods. The Medication Adherence Scale in FMF Patients (MASIF) is a 18-item questionnaire that evaluates adherence to medication in four domains. Validation of the instrument was accomplished in paediatric FMF patients (aged 2-18 years) under medication at least for 6 months. The first step was to build up the scale through qualitative approach (with interviews using semi-structured questions). Validation analyses included assessment of feasibility, face and content validity; construct validity, internal consistency and test-retest reliability.
Results. One hundred and fifty patients with FMF were enrolled in the study. The mean age of the patients was 11.11 +/- 4.02 years and 48.7% of them were male. The MASIF was found to be feasible and valid for both face and content. It correlated with the Morisky Medication Adherence Scale as a gold standard thereby demonstrating good construct validity (r=0.5 15, p<0.001). Assessment of content validity identified four subscales. The internal consistency, Cronbach's alpha was 0.728. There was a positive and significant correlation between test and retest scores (r-0.843; p<0.001). Also, a significant correlation between parents' and children's reports (r=0.781, p<0.001).
Conclusion. Based on these results, the use of this scale to assess and follow up the adherence to treatment in paediatric FMF patients under medical treatment is recommended.
C1 [Yesilkaya, S.; Sari, O.; Aydogan, U.; Ozenc, S.] Gulhane Mil Med Acad, Dept Family Med, Ankara, Turkey.
[Acikel, C.] Gulhane Mil Med Fac, Dept Biostat, TR-06018 Ankara, Turkey.
[Fidanci, B. E.] Gulhane Mil Med Acad, Sch Nursing, Ankara, Turkey.
[Polat, A.; Simsek, D.; Saldir, M.; Fidanci, K.; Basbozkurt, G.] Gulhane Mil Med Fac, Dept Paediat, Ankara, Turkey.
[Sozeri, B.; Berdeli, A.] Ege Univ, Fac Med, Paediat Rheumatol, Izmir, Turkey.
[Ayaz, N. A.] Kanuni Sultan Suleyman Res & Training Hosp, Paediat Nephrol Rheumatol, Istanbul, Turkey.
[Makay, B. B.; Kavukcu, S.; Unsal, E.] Dokuz Eylul Univ Hosp, Dept Paediat, Izmir, Turkey.
[Akinci, N.; Ozcelik, G.] Sisli Etfal Educ & Res Hosp, Dept Paediat, Istanbul, Turkey.
[Emre, S.; Kasapcopur, O.] Istanbul Univ, Dept Paediat, Istanbul, Turkey.
[Donmez, O.] Uludag Univ, Dept Paediat Rheumatol, Fac Med, Bursa, Turkey.
[Delibas, A.] Akdeniz Univ, Dept Paediat, Mersin, Turkey.
[Yuksel, S.] Pamukkale Univ, Dept Paediat, Fac Med, Denizli, Turkey.
[Poyrazoglu, H.] Erciyes Univ, Fac Med, Dept Paediat, Kayseri, Turkey.
[Cakar, N.] Minist Hlth, Diskapi Childrens Hosp, Paediat Nephrol, Ankara, Turkey.
[Peru, H.] Selcuk Univ, Dept Paediat, Ankara, Turkey.
[Bakkaloglu, S.] Gazi Univ, Dept Paediat, Ankara, Turkey.
[Tabel, Y.] Inonu Univ, Paediat Nephrol, Malatya, Turkey.
[Ozen, S.] Hacettepe Univ, Paediat Nephrol & Rheumatol Unit, Ankara, Turkey.
[Gok, F.; Demirkaya, E.] Gulhane Mil Med Fac, Paediat Rheumatol Unit, Ankara, Turkey.
[Demirkaya, E.] Gulhane Mil Med Acad, FMF Arthrit Vasculitis & Orphan Dis Res Paediat R, Ankara, Turkey.