dc.contributor.author |
Çolak, Cemil |
|
dc.contributor.author |
Ercan, İlker |
|
dc.contributor.author |
Doğan, Metin |
|
dc.contributor.author |
Özdemir, Senem Turan |
|
dc.contributor.author |
Şener, Serpil |
|
dc.contributor.author |
Alkan, Alpay |
|
dc.date.accessioned |
2018-01-09T07:18:56Z |
|
dc.date.available |
2018-01-09T07:18:56Z |
|
dc.date.issued |
2011 |
|
dc.identifier.citation |
Colak, C., Ercan, I., Dogan, M., Ozdemir, Senem T., Sener, S., Alkan, A. (2011). Detecting the shape differences of the corpus callosum in behçet s disease by statistical shape analysis. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. |
tr_TR |
dc.identifier.uri |
http://onlinelibrary.wiley.com/doi/10.1002/ar.21373/epdf |
|
dc.identifier.uri |
http://hdl.handle.net/11616/7962 |
|
dc.description |
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology |
tr_TR |
dc.description.abstract |
The aim of this study was to assess the shape differences of the cor-pus callosum (CC) in patients with Behc¸et’s disease using statisticalshape analysis (SSA). Additionally, an attempt was made to investigatethe changes in CC size according to disease duration. Twenty-five adultswith clinically diagnosed Behc¸et’s disease and 25 age- and gender-matched controls were examined by high-resolution structural magneticresonance imaging. The data obtained from the coordinate of landmarkswere analyzed with Euclidean distance matrix analysis and a thin-platespline analysis. SSA and growth curve models were performed to investi-gate group differences and to fit the curves. A significant difference wasdetermined between CC shape of Behc¸et patients and controls (P ¼0.006). Based on the analysis, a decrease occurred in the CC size of theBehc¸et patients as the duration of disease increased. Maximum deforma-tions were determined in the landmarks of interior notch of the splenium,inferior tip of the splenium, posterior-most point of the CC, and topmostpoint of the CC. Similarly, the landmark of anterior-most point of the CCwas identified as having the minimum deformation. Behc¸et patients hadsignificantly different CC shapes from control subjects. The results sug-gest that SSA is a promising tool for distinguishing Behc¸et patients fromnormal subjects, and that it can give useful information to assist clini-cians. Additionally, SSA might be applied to detect shape differences inanatomical structures that are affected by a broad range of neurologicaldiseases. Anat Rec, 294:870–874, 2011.VVC2011 Wiley-Liss, Inc. |
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dc.language.iso |
eng |
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dc.publisher |
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology |
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dc.relation.isversionof |
10.1002/ar.21373 |
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dc.rights |
info:eu-repo/semantics/openAccess |
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dc.subject |
Behcet diaeses |
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dc.subject |
Corpus callosum |
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dc.subject |
Geometricmorphometrics |
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dc.subject |
Growth curve models |
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dc.subject |
Statisticalshape analysis |
tr_TR |
dc.title |
Detecting the shape differences of the corpus callosum in behçet s disease by statistical shape analysis |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.journal |
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology |
tr_TR |
dc.contributor.department |
İnönü Üniversitesi |
tr_TR |
dc.contributor.authorID |
9712 |
tr_TR |
dc.contributor.authorID |
19524 |
tr_TR |
dc.identifier.volume |
0 |
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dc.identifier.issue |
0 |
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dc.identifier.startpage |
0 |
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dc.identifier.endpage |
0 |
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