dc.contributor.author |
Yılmaz, Sezai |
|
dc.contributor.author |
Aydın, Cemalettin |
|
dc.contributor.author |
Işık, Burak |
|
dc.contributor.author |
Kayaalp, Cüneyt |
|
dc.contributor.author |
Yılmaz, Mehmet |
|
dc.contributor.author |
Ara, Cengiz |
|
dc.contributor.author |
Kutlu, Ramazan |
|
dc.contributor.author |
Bayındır, Yaşar |
|
dc.contributor.author |
Ersan, Veysel |
|
dc.date.accessioned |
2018-02-06T11:53:43Z |
|
dc.date.available |
2018-02-06T11:53:43Z |
|
dc.date.issued |
2013 |
|
dc.identifier.citation |
S. Yılmaz Et Al., “Abo İncompatible Liver Transplantation İn Acute And Acute On Chronic Liver Failure ,” Hepatogastroenterology, Pp. 0–0, 2013. |
tr_TR |
dc.identifier.uri |
https://www.ncbi.nlm.nih.gov/pubmed/23478144 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/8044 |
|
dc.description |
Hepatogastroenterology. 2013 Jul-Aug;60(125):1189-93. |
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dc.description.abstract |
Abstract
BACKGROUND/AIMS:
ABO-incompatible (ABO-I) liver transplantation (LTx) may be mandatory in urgent conditions such as acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) when deceased donor (DD) is unavailable or living donor (LD) selection is limited. This study specifically addresses the problem of urgent ABO-I LTx in critically ill adult patients having ALF or severely decompensated end-stage liver disease.
METHODOLOGY:
This series included 16 patients, 10 underwent ABO-I LD LTx and 6 underwent 7 ABO-I DD LTx. Multiple sessions of plasmapheresis reduced isoaglutinin titres to 1/16 or below, before and after LTx.
RESULTS:
Mean follow-up period was 10.37 months (1 to 38). Median for MELD scores was 22.5 (17 to 30). Median survival was 9 months and mean survival was 19.5 months. Hospital mortality was 3 (18.7%). Two patients died due to small for size graft syndrome and cerebrovascular bleeding respectively. Hepatic artery thrombosis developed in 3 patients. Two of them died at postoperative 4th and 9th months. Third patient is still alive with hepatic necrosis problem.
CONCLUSIONS:
ABO-I LTx remains an important and unavoidable therapeutic option in adult patients with ALF or ACLF and urgent need for an allograft without the possibility to allocate a blood group compatible liver graft. |
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dc.language.iso |
eng |
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dc.publisher |
Hepatogastroenterology |
tr_TR |
dc.rights |
info:eu-repo/semantics/openAccess |
tr_TR |
dc.title |
ABO incompatible liver transplantation in acute and acute on chronic liver failure |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.journal |
Hepatogastroenterology |
tr_TR |
dc.contributor.department |
İnönü Üniversitesi |
tr_TR |
dc.identifier.volume |
0 |
tr_TR |
dc.identifier.issue |
0 |
tr_TR |
dc.identifier.startpage |
0 |
tr_TR |
dc.identifier.endpage |
0 |
tr_TR |