dc.contributor.author |
Cicek, D |
|
dc.contributor.author |
Pekdemir, H |
|
dc.contributor.author |
Kalay, N |
|
dc.contributor.author |
Binici, S |
|
dc.contributor.author |
Altay, H |
|
dc.contributor.author |
Muderrisoglu, H |
|
dc.date.accessioned |
2022-10-19T08:16:33Z |
|
dc.date.available |
2022-10-19T08:16:33Z |
|
dc.date.issued |
2010 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/82082 |
|
dc.description.abstract |
Background: The efficacy of drug-eluting stents has been shown in randomized trials, but some controversy exists regarding which stent sirolimus-eluting or paclitaxel-eluting is more effective in unselected Turkish patients. Therefore, we investigated the clinical outcomes of patients who were treated with one type of these drug-eluting stents in the real world. |
|
dc.description.abstract |
Methods: We created a registry and prospectively analyzed data on a consecutive series of all patients who presented to our institution with symptomatic coronary artery disease between February 2005 and March 2007 and who were treated with the sirolimus- or the paclitaxel-eluting stent. The follow-up period after stent implantation was approximately 24 months. The primary end point was a major cardiac event, and the secondary end point was stent thrombosis. Informed consent was obtained from all subjects, and the study protocol was approved by the local ethical committee. |
|
dc.description.abstract |
Results: In total, 204 patients were treated with either the sirolimus-eluting stent (n = 103) or the paclitaxel-eluting stent (n = 101). The lesions in the 2 arms of the study were treated similarly by conventional technique. At 24-month follow-up, patients who received the paclitaxel-eluting stent showed significantly higher rates of non-Q-wave myocardial infarction (1.9% vs 5.9%; P: .002), target vessel revascularization (1.9% vs 4.9%; P: .002), coronary artery bypass graft surgery (1.9% vs 6.9%; P: .001), and late stent thrombosis (1.9% vs 3.9%, P: .002). |
|
dc.description.abstract |
Conclusions: Patients who received the sirolimus- eluting stent showed better clinical outcomes compared with those who had the paclitaxel-eluting-stent. |
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dc.description.abstract |
C1 [Cicek, Davran] Baskent Univ, Sch Med, Dept Cardiol, Antalya, Turkey. |
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dc.description.abstract |
[Pekdemir, Hasan] Inonu Univ, Sch Med, Dept Cardiol, Malatya, Turkey. |
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dc.description.abstract |
[Kalay, Nihat] Erciyes Univ, Sch Med, Dept Cardiol, Kayseri, Turkey. |
|
dc.description.abstract |
[Binici, Sueleyman; Altay, Hakan] Erciyes Univ, Sch Med, Dept Cardiol, Adana, Turkey. |
|
dc.description.abstract |
[Muderrisoglu, Haldun] Baskent Univ, Sch Med, Dept Cardiol, TR-06490 Ankara, Turkey. |
|
dc.source |
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES |
|
dc.title |
Efficacy of Sirolimus-Eluting Stents Compared With Paclitaxel-Eluting |
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dc.title |
Stents in an Unselected Population With Coronary Artery Disease: |
|
dc.title |
24-Month Outcomes of Patients in a Prospective Non-randomized Registry |
|
dc.title |
in Southern Turkey |
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