| dc.contributor.author |
Ara, C |
|
| dc.contributor.author |
Esrefoglu, M |
|
| dc.contributor.author |
Polat, A |
|
| dc.contributor.author |
Isik, B |
|
| dc.contributor.author |
Aladag, M |
|
| dc.contributor.author |
Gul, M |
|
| dc.contributor.author |
Ay, S |
|
| dc.contributor.author |
Tekerleklioglu, MS |
|
| dc.contributor.author |
Yilmaz, S |
|
| dc.date.accessioned |
2022-10-19T12:04:53Z |
|
| dc.date.available |
2022-10-19T12:04:53Z |
|
| dc.date.issued |
2006 |
|
| dc.identifier.uri |
http://hdl.handle.net/11616/83111 |
|
| dc.description.abstract |
We investigated the effect of caffeic acid phenethyl ester in rat ileum injury induced by chronic biliary obstruction. Swiss albino rats were divided into three groups: Group 1, sham (n = 7); Group 2, common bile duct ligation (n = 7); and Group 3, common bile duct ligation plus caffeic acid phenethyl ester (n = 7). In the caffeic acid phenethyl ester-treated rats, ileum tissue levels of malondialdehyde and myeloperoxidase were significantly lower than those of the bile duct-ligated rats (P < 0.001). The levels of tumor necrosis factor-alpha, interleukin-6, and interleukin-1 alpha in the caffeic acid phenethyl ester group were significantly lower than those in the bile duct ligation group (P < 0.03, P < 0.01, and P < 0.02 respectively). The present study demonstrates that intraperitoneal administration of caffeic acid phenethyl ester in bile duct-ligated rats reduces intestinal oxidative stress. This effect may be useful in the preservation of intestinal damage in cholestasis. |
|
| dc.description.abstract |
C1 Inonu Univ, Sch Med, Dept Gen Surg, TR-44069 Malatya, Turkey. |
|
| dc.description.abstract |
Inonu Univ, Sch Med, Dept Histol & Embryol, TR-44069 Malatya, Turkey. |
|
| dc.description.abstract |
Inonu Univ, Sch Med, Dept Physiol, TR-44069 Malatya, Turkey. |
|
| dc.description.abstract |
Inonu Univ, Sch Med, Dept Gastroenterol, TR-44069 Malatya, Turkey. |
|
| dc.description.abstract |
Inonu Univ, Sch Med, Dept Med Microbiol, TR-44069 Malatya, Turkey. |
|
| dc.source |
DIGESTIVE DISEASES AND SCIENCES |
|
| dc.title |
The effect of caffeic acid phenethyl ester on bacterial translocation |
|
| dc.title |
and intestinal damage in cholestatic rats |
|