A highly effective, easy to handle, and environmentally benign process for palladium-mediated Suzuki cross-coupling was developed. The in situ prepared three-component system of Pd(OAc)(2), 1,3-dialkyltetrahydrodiazepinium chlorides (2a-e), and K2CO3 catalyzes quantitatively the Suzuki-Miyaura cross-coupling of deactivated aryl chloride.
C1 Inonu Univ, Fac Sci & Arts, Dept Chem, TR-44280 Malatya, Turkey.
Ege Univ, Dept Chem, TR-35100 Izmir, Turkey.