dc.contributor.author |
Ozdemir, I |
|
dc.contributor.author |
Denizci, A |
|
dc.contributor.author |
Ozturk, HT |
|
dc.contributor.author |
Cetinkaya, B |
|
dc.date.accessioned |
2022-10-19T12:13:21Z |
|
dc.date.available |
2022-10-19T12:13:21Z |
|
dc.date.issued |
2004 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/84108 |
|
dc.description.abstract |
Six new 1,3-diorganylimidazolidin-2-ylidene (NHC) gold(I) complexes of the type [Au(NHC)(2)](+) (1-6), were synthesized by reacting [AuCl(PPh)(3)] with 1,3-dimesitylimidazolidin-2-ylidene or bis(1,3-dialkylimidazolidin-2-ylidene). The complexes 1-6 were fully characterized by elemental analyses and spectroscopic data. The placement of mesityl or para-substituted benzyl groups on the nitrogen atoms of the ring of the complexes leads to the particularly active antibacterial agents evaluated in this work. It is worth noting that the p-methoxybenzyl derivative (2) inhibited the growth of Pseudomona aeruginosa, Staphylococcus epidermidis, Staphylococcus aureus and Enterococcus faecalis with minimum inhibitory concentration (MIC) values of 3.12 mug ml(-1), 6.25 mug ml(-1), 3.12 mug ml(-1) and 3.12 mug ml(-1) respectively. In contrast, the analogous p-dimethylaminobenzyl derivative (3) is effective only against Escherichia coli (MIC = 3.12 mug ml(-1)). Copyright (C) 2004 John Wiley Sons, Ltd. |
|
dc.description.abstract |
C1 Ege Univ, Dept Chem, TR-35100 Izmir, Turkey. |
|
dc.description.abstract |
Ege Univ, Dept Microbiol, TR-35100 Izmir, Turkey. |
|
dc.description.abstract |
Inonu Univ, Dept Chem, Malatya, Turkey. |
|
dc.source |
APPLIED ORGANOMETALLIC CHEMISTRY |
|
dc.title |
Synthetic and antimicrobial studies on new gold(I) complexes of |
|
dc.title |
imidazolidin-2-ylidenes |
|