Görmeli, GökayGörmeli, Cemile AyşeAtaoğlu, BaybarsÇolak, CemilAslantürk, OkanErtem, Kadir2017-12-202017-12-202015Gökhan, G., Görmeli, C. A., Ataoğlu, M. B., Çolak, C., & Aslantürk, O. (2015). Multiple Prp İnjections Are More Effective Than Single İnjections And Hyaluronic Acid İn Knees With Early Osteoarthritis A Randomized Double Blind Placebo Controlled Trial. Knee Surgery, Sports Traumatology, Arthroscopy, 0–0.https://link.springer.com/content/pdf/10.1007%2Fs00167-015-3705-6.pdfhttps://hdl.handle.net/11616/7913Knee Surgery, Sports Traumatology, Arthroscopy, 0–0.Purpose To compare the effectiveness of intraarticular (IA) multiple and single platelet-rich plasma (PRP) injections as well as hyaluronic acid (HA) injections in different stages of osteoarthritis (OA) of the knee. Methods A total of 162 patients with different stages of knee OA were randomly divided into four groups receiving 3 IA doses of PRP, one dose of PRP, one dose of HA or a saline injection (control). Then, each group was subdivided into two groups: early OA (Kellgren–Lawrence grade 0 with cartilage degeneration or grade I–III) and advanced OA (Kellgren–Lawrence grade IV). The patients were evaluated before the injection and at the 6-month followups using the EuroQol visual analogue scale (EQ-VAS) and International Knee Documentation Committee (IKDC) subjective scores. Adverse events and patient satisfaction were recorded.eninfo:eu-repo/semantics/openAccessHyaluronic acidIntraarticular injectionKnee osteoarthritisPlatelet-rich plasmaMultiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis a randomized double blind placebo controlled trialArticle0000