A down syndrome patient diagnosed with transient myeloproliferative disease after presenting with cutaneous findings

Ceran, BurakDerme, TuranErkan, Mehmet OrhanSahin, SedaGurlek Gokcebay, DilekCakir, UfukTayman, Cuneyt2022-03-152022-03-152021Ceran, B., Derme, T., Erkan, M. O., Sahin, S., Gokcebay, D. G., Cakir, U., & Tayman, C. (2021). A down syndrome patient diagnosed with transient myeloproliferative disease after presenting with cutaneous findings. Annals of Medical Research,https://hdl.handle.net/11616/55601Transient myeloproliferative disease (TMD) is among the main hematologic problems seen in neonates with Down syndrome (DS). It is usually self-limiting and results in spontaneous remission within 3 to 6 months. Characteristic signs of TMD are leukocytosis, thrombocytopenia, anemia, hepatosplenomegaly, cutaneous nodules, and increased numbers of circulating blasts. In this article, we present a DS neonate without leukocytosis who was diagnosed as having TMD after a diffuse vesiculopapular eruption on the face, which is a different clinical presentation than other cases in the literature. Our aim is to emphasize the importance of early diagnosis and close multidisciplinary monitoring of these patients.eninfo:eu-repo/semantics/openAccessA down syndrome patient diagnosed with transient myeloproliferative disease after presenting with cutaneous findingsArticle