Ezugwu, James AnayochukwuKucukbay, Hasan2026-04-042026-04-0420241551-70041551-7012https://doi.org/10.24820/ark.5550190.p012.429https://hdl.handle.net/11616/108774L-Amino acids were converted into sulfonamides by reaction with phenylsulfonyl chloride in a basic medium. Subsequent treatment of these sulfonamides with 1H-benzotriazole (BtH) and thionyl chloride at room temp erature yielded benzotriazole-amino acid-benzenesulfonamide conjugates with yields ranging from 42% to 68%. Furthermore, the reaction of the benzotriazole derivatives with free glycine and free phenylalanine resulted in the formation of (phenylsulfonyl)dipeptides.eninfo:eu-repo/semantics/openAccessBenzensulfonamidebenzotriazoleL-amino acidssynthesisArticle10.24820/ark.5550190.p012.4292-s2.0-105030822101Q4WOS:001667189800001Q4