Ekinci, EKaragozler, AAKaragozler, AE2024-08-042024-08-0419961040-0397https://doi.org/10.1002/elan.1140080613https://hdl.handle.net/11616/92972An amperometric biosensor for glucose based on a novel polymeric matrix is described. The sensor was prepared by electrochemical polymerization of p-aminophenol in the presence of glucose oxidase on Pt substrates in a KCl solution at a potential of 0.6 V (vs. Ag/AgCl). The chronoamperometric response of poly(p-aminophenol)-glucose oxidase biosensor to hydrogen peroxide formed as the result of enzymatic reaction was measured at a potential of 0.7 V (vs. Ag/AgCl) in PBS solution. It was shown that a biosensor prepared by this onestep procedure has a linear range up to 6 mM glucose, a response time less than 5 s and a lifetime around 15 days. The sensitivity of the electrode was superior to that of much publicized polypyrrole based glucose oxidase electrode. Also, the substrate selectivity of PAP/GOx electrode was tested for coexisting substances such as lactose, sucrose, urea, paracetamol, uric and ascorbic acid and no discernible anodic response was observed above the background current.eninfo:eu-repo/semantics/closedAccessglucoseglucose oxidasepoly(p-aminophenol)enzyme electrodeamperometric biosensorArticle8657157410.1002/elan.11400806132-s2.0-0000830321N/AWOS:A1996UW69200012N/A