Karataş, Mert OlgunErgün, Adem2021-12-292021-12-292019KARATAŞ M. O,ERGÜN A (2019). Synthesis, Characterization, and Carbonic Anhydrase Inhibitory Properties of Silver(I) Complexes of Benzimidazole Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, 6(2), 253 - 260. Doi: 10.18596/jotcsa.5469602149-0120https://doi.org/10.18596/jotcsa.546960https://hdl.handle.net/11616/44675https://search.trdizin.gov.tr/yayin/detay/396234Abstract: The antimicrobial properties of silver compounds and biological properties ofbenzimidazole derivatives have been well known for many years. In the present study, in terms oftheir biological potential, six novel silver(I)-N-alkylbenzimidazole derivatives were synthesized inorder to examine their carbonic anhydrase (CA) inhibitory properties. All complexes werecharacterized by the combination of 1H NMR, 13C NMR, mass, FT-IR spectroscopic methods andelemental analyses. The inhibitory properties of all complexes were tested on the esterase activityof human CA I and II (hCA I and hCA II). Acetazolamide was used as a standard. All complexesinhibited the hCA I and hCA II activity in the range of 27.37-29.58 µM and 20.93-27.25 µM,respectively.eninfo:eu-repo/semantics/openAccessArticle6225326010.18596/jotcsa.5469602-s2.0-85070517421N/A396234