Slimani, IchrafMansour, LamjedOzdemir, IsmailGurbuz, NevinHamdi, Naceur2024-08-042024-08-0420210020-16931873-3255https://doi.org/10.1016/j.ica.2020.120043https://hdl.handle.net/11616/99570Eight benzimidazolium salts (2a-h) with two nitrogen atoms substituted by various alkyl groups have been synthesized in high yields. The benzimidazolium salts were readily converted into the corresponding PEPPSItype palladium-NHC complexes (PEPPSI = pyridine-enhanced precatalyst preparation, stabilization, and initiation) (3a-h). The structures of all compounds were characterized by H-1 NMR, C-13 NMR, and IR spectroscopy as well as by elemental analysis techniques, which support the proposed structures. The catalytic activity of the PEPPSI-type palladium-NHC complexes was evaluated with respect to the direct C5-arylation of 2-substituted heteroaryl derivatives (thiophene, furan and thiazole) with various aryl bromides. This arylation occurs efficiently and selectively at the C5-position of the 2-substituted thiophene, furan and thiazole derivatives.eninfo:eu-repo/semantics/closedAccessN-Heterocyclic carbenePEPPSI-type palladium-NHC complexesBenzimidazolium saltsDirect arylationArticle51510.1016/j.ica.2020.1200432-s2.0-85092108454Q2WOS:000598922900006Q2