Kekilli, EYagmur, CKuzucu, ASoysal, OCikim, ASErtem, K2024-08-042024-08-0420040914-71871864-6433https://doi.org/10.1007/BF02984586https://hdl.handle.net/11616/93751Fibrous dysplasia of bone is a congenital, sporadic developmental disorder characterized by immature fibrous connective tissue and bone deformities. Hepatic Tc-99m-MDP uptake is a rare, serendipitous finding during bone scanning studies. The present patient was a 25-year-old male who had severe polyostotic fibrous dysplasia. On Tc-99m-MDP (methylene diphosphonate) bone scintigraphy, increased activity accumulations were seen on multiple ribs, vertebrae and base of the cranium. In addition, diffuse increased pathologic uptake of Tc-99m-MDP in the liver was shown. Intravenous pamidronate was administered monthly for two months. In the third week of the last administration Tc-99m-MDP bone scintigraphy was performed again, but despite sustained bone involvement, pathologic hepatic uptake was not seen on the scan. We thought that pathologic hepatic Tc-99m-MDP accumulation, may be related to the formation and aggregation of calcium oxalate and phosphate crystals which improved with pamidromat treatment.eninfo:eu-repo/semantics/closedAccessfibrous dysplasiahepaticextra-osseousArticle1876276301558663810.1007/BF029845862-s2.0-10044276208Q2WOS:000225205600011Q4