Tasolar, S. D.Sigirci, A.Ciftci, N.Cengiz, A.Dogan, G. M.Akinci, A.2024-08-042024-08-0420231128-3602https://hdl.handle.net/11616/101650- OBJECTIVE: Although there is a relationship between earlier onset of puberty and increased adiposity tissue. Publications in the lit-erature on adiposis in patients with central pre-cocious puberty (CPP) and visceral fat thickness (VFT) have conflicting results. So, in this study, we aimed to evaluate the relationship between sexual maturation and obesity in the development of early puberty and to examine their relationship with pelvic sonographic parameters. PATIENTS AND METHODS: A total of 126 girls [patients - premature thelarche (PT) and CPP - and controls] were included in this study. Anthro-pometric and ultrasonographic evaluations were made by the same pediatric endocrinologist and pediatric radiologist, respectively. Pubertal stages were made according to the Tanner stages. Height, weight, and body mass index were measured as anthropometric measurements, and visceral, sub-cutaneous, and transabdominal fat thicknesses were measured in sonographic evaluation. RESULTS: The study population was divided in-to three groups: 44 healthy subjects to Group 1, 23 patients with PT to Group 2, and 59 patients with CPP to Group 3. When we evaluated the anthropo-metric and ultrasonographic parameters according to pubertal status, significant differences, especial-ly between Group 1 and Group 3, were observed in all data. In the multiple logistic regression analysis, the endometrial thickness (OR = 7.521, p < 0.001) and VFT (OR = 1.530, p < 0.001) were found to be in-dependent predictors of precocious puberty. CONCLUSIONS: It has been found that VFT and endometrial thickness measurements, which are evaluated quickly and accurately by USG, are im-portant predictors of prepubertal precociousness.eninfo:eu-repo/semantics/closedAccessObesityCentral precocious pubertyVisceral thicknessUltrasonographyArticle271992269233378433362-s2.0-85175586051Q2WOS:001096798300028N/A