Sahin, NurhanBozdag, ZehraErkilic, SunaAydin, Nasuhi EnginSener, Serpil2024-08-042024-08-0420162717-63982651-5164https://doi.org/10.4274/turkderm.53765https://hdl.handle.net/11616/97515Background and Design: Actinic (solar) keratosis (AK) is a precancerous, epidermal lesion, which develops in sensitive skin exposed to sun for a long period. AKs are divided into different histopathological subtypes. There is a link between the clinical progression of the histopathological subtypes, the degree of cellular atypia, and the precancerous nature of the lesion. Different series have reported that the rate of transformation of AK to squamous cell carcinoma (SCC) ranges between 12% and 20%. Materials and Methods: In this study, we reevaluated patients who were diagnosed with AK in the Pathology Departments of the Medical Faculties of Inonu and Gaziantep Universities over an eight-year period, and divided the patients into different histopathological subtypes. In addition, we investigated the association between the lesions, and basal cell carcinoma (BCC), SCC and both carcinomas. Results: 29,6% of cases were proliferative AK, 27% of cases were hypertrophic AK. 19% and 13% of all lesions was associated with BCC and SCC, respectively. Conclusion: In this study, we found that the most frequent subtype was proliferative AK and the most frequent nonmelanotic skin cancer was BCC associated with AK.trinfo:eu-repo/semantics/openAccessActinic keratosissolar keratosishistopathologynon melanotic skin cancersArticle50310310810.4274/turkderm.537652-s2.0-84988874551Q4WOS:000388299400004N/A