Sahin, NeslihanDusunceli, Serpil DemirOzdemir, Ismail2024-08-042024-08-0420170385-54141881-0942https://doi.org/10.3987/COM-17-13737https://hdl.handle.net/11616/97906Aminoarenes constitute valuable building blocks in organic synthesis and an essential skeleton ubiquitously found in ligands, agrochemicals, and pharmaceuticals. This synopsis presents recent amination methods using nitrogen-heteroatom bonds as a powerful and versatile platform to rapidly synthesize diverse aminoarenes, with transition-metal catalyzed arene C-H amination. The Buchwald-Hartwig amination has been investigated theoretically and experimentally to examine the scope of possible bases under different reaction conditions. We report examples of the palladium NHC (N-heterocyclic carbene) catalyzed amination of aryl halides with anilines and amines in the presence of dimethoxyethane solvent and potassium tertiary-butoxide as a base.eninfo:eu-repo/semantics/openAccessCross-Coupling ReactionsOlefin Metathesis CatalystsPalladium ComplexesSuzuki-MiyauraStructural-CharacterizationMetal-ComplexesAminationHalidesArylLigandsArticle9481506151710.3987/COM-17-137372-s2.0-85026304095Q4WOS:000408301300006Q4