Deniz, Sahin KenanTurgut, HaticeDeveci, FatihKaya, HueseyinGokce, Ismail KursadOzdemir, RamazanOnal, Selami Cagatay2026-04-042026-04-0420240303-84671872-6968https://doi.org/10.1016/j.clineuro.2024.108577https://hdl.handle.net/11616/109676Objective: Despite advances, myelomeningocele remains a major cause of mortality and disability. This study aims to analyze factors influencing mortality and suggest ways to reduce it. Methods: We reviewed 173 patients who underwent surgery for myelomeningocele from January 2010 to December 2021. Variables affecting mortality were categorized into patient-related and indirectly related factors. Data were collected through patient file reviews and phone interviews with parents. Results: Mortality is influenced by multiple factors: female gender (3.2-fold increase), paraplegia (3.1-fold increase), absence of tethered cord release surgery (9.4-fold increase), scoliosis (4.2-fold increase), and renal failure (5.28-fold increase). Defect size and father's education level also significantly impact mortality. The overall mortality rate was 20.8 %, with hydrocephalus being the leading cause. Conclusion: Mortality and disability in myelomeningocele patients remain high, with over 50 % of deaths being preventable. Effective management could significantly improve mortality rates. Long-term studies are crucial for advancing research in this field.eninfo:eu-repo/semantics/closedAccessLong-term outcomeMortality predictorsMortality ratesMyelomeningoceleArticle2463938358310.1016/j.clineuro.2024.1085772-s2.0-85205693086Q2WOS:001332968200001Q30000-0002-3328-41560000-0002-0490-78520000-0001-8952-28650000-0002-9177-69410000-0003-4722-1188