Bilgic, Y.Harputluoglu, M. M. M.Kutlu, O.Demirel, U.Gul, M.Otlu, B.Temel, I.2024-08-042024-08-0420151721-727Xhttps://doi.org/10.1177/1721727X15618413https://hdl.handle.net/11616/97077Background and study aim: The aim of the present study was to investigate the effects of Lycium barbarum (LB) on bacterial translocation (BT) frequency in thioacetamide (TAA)-induced liver injury in rats. Materials and methods: Group 1 was the control. In group 2 (TAA), rats received TAA daily for 3 days. In group 3 (TAA+LB), Lycium barbarum was administered orally 25 mg/kg for 21 days prior to the first TAA injection. In group 4 (LB), rats received only Lycium barbarum. Results: In our study, Lycium barbarum treatment did not attenuate liver damage. Lycium barbarum treatment decreased ileal E. coli counts and intestinal damage but it did not alter BT frequency. Conclusions: In conclusion, the effects of Lycium barbarum on BT may be related to ongoing severe liver damage in this model.eninfo:eu-repo/semantics/openAccessbacterial translocationliver injuryLycium barbarumthioacetamideArticle13315416310.1177/1721727X156184132-s2.0-84949219401N/AWOS:000365744100003Q4