Kamişli Ö.Gönüllü S.Kamişli S.Kaplan Y.Özcan C.2024-08-042024-08-0420131301-1375https://doi.org/10.5505/tbdhd.2013.52724https://hdl.handle.net/11616/91322OBJECTIVE: Uric acid is a water-soluble antioxidant which is the end-product of purine metabolism. Several studies indicated that high levels of serum uric acid increased the risk of cerebrovascular events and some of them reported poor prognosis with increased serum uric acid levels in stroke patients. Our aim was to analyse serum uric acid levels in the early phase of ischemic stroke and determine whether increased levels of uric acid are associated with ischemic stroke subtypes. MATERIAL and METHODS: 237 patients with ischemic stroke admitted to the study between January 2011 and December 2011. Ischemic stroke subtypes were classified according to Bamford classification. Patients admitted in the the beginning of the first 24 hour of disease were included the study. We compare the serum uric acid levels between stroke subgroups and controls. RESULTS: We found increased serum uric acid levels in all stroke patients but the most increased levels were in the posterior circulation infarct group. However this elevation was not statistically significant. CONCLUSION: Future researches should be focus on the pathogenetic mechanism of hyperuricemia as well as examining the role in stroke subtypes especially posterior circulation infarcts.trinfo:eu-repo/semantics/openAccessBamford classificationIschemic strokeUric acidArticle19171010.5505/tbdhd.2013.527242-s2.0-84884489110N/A