Elkıran, ÖzlemKarakurt, CemşitKoçak, GülemdarTabel, YılmazGüngör, Serdal2018-01-182018-01-182015Ö. Elkıran, C. Karakurt, G. Koçak, Y. Tabel, And S. Güngör, “Possible Association Between Fluconazole Administration And Acute Hyperkalemia İn A Critically İll Cyanotic İnfant ,” Arch Med Sci, Vol. 11, No. 1, Pp. 235–6, 2015.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379377/pdf/AMS-11-24661.pdfhttps://hdl.handle.net/11616/7998Arch Med Sci 2015; 11, 1: 235–236Fluconazole, an azole antifungal agent, inhibits the fungal cytochrome P450 enzyme. Although in vitro data show that fluconazole is not a potent inhibitor of mammalian P450 enzymes, hyperkalemia secondary to adrenal insufficiency associated with fluconazole has been described rarely [1–3]. However, life-threatening severe hyperkalemia related to administration of intravenous fluconazole without adrenal suppression has not been reported before.eninfo:eu-repo/semantics/openAccessArticle111235236