Karaca, Emine OzgeAkkoc, MitatTahir, Muhammad NawazArici, CengizImik, FatmaGurbuz, NevinYasar, Sedat2024-08-042024-08-0420170040-4039https://doi.org/10.1016/j.tetlet.2017.07.096https://hdl.handle.net/11616/97917A series of seven-membered ditopic ring-expanded N-heterocyclic carbene (dre-NHC) precursors, bearing sterically demanding and electron-rich aryl groups, were synthesised in moderate yields via the reaction of 1,2,4,5-tetrakis(bromomethyl)benzene with the corresponding N,N'-diarylformamidines in the presence of K2CO3 in acetonitrile under an air atmosphere. All new compounds were characterised by HRMS, NMR spectroscopy, and microanalysis, as well as X-ray crystallography for compound lc. The development of an efficient catalytic system for the Suzuki-Miyaura coupling reaction of aryl chlorides with various boronic acids was also investigated using the in situ generated dre-NHC ligands. (C) 2017 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessDitopic ring-expanded N-heterocyclic carbeneSuzuki-Miyaura couplingC-C bond formationPalladiumArticle58363529353210.1016/j.tetlet.2017.07.0962-s2.0-85026795462Q3WOS:000409153900011Q2